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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1976 1
1977 1
1979 2
1980 1
1983 1
1984 2
1985 1
1987 5
1988 2
1989 5
1990 4
1991 2
1992 2
1993 3
1994 1
1995 6
1996 2
1997 1
1998 4
1999 2
2000 3
2001 5
2002 5
2003 5
2004 5
2005 6
2006 6
2007 6
2008 6
2009 12
2010 11
2011 11
2012 10
2013 15
2014 15
2015 8
2016 13
2017 13
2018 14
2019 12
2020 9
2021 14
2022 17
2023 13
2024 7

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266 results

Results by year

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Page 1
Single-cell multi-omics analysis of the immune response in COVID-19.
Stephenson E, Reynolds G, Botting RA, Calero-Nieto FJ, Morgan MD, Tuong ZK, Bach K, Sungnak W, Worlock KB, Yoshida M, Kumasaka N, Kania K, Engelbert J, Olabi B, Spegarova JS, Wilson NK, Mende N, Jardine L, Gardner LCS, Goh I, Horsfall D, McGrath J, Webb S, Mather MW, Lindeboom RGH, Dann E, Huang N, Polanski K, Prigmore E, Gothe F, Scott J, Payne RP, Baker KF, Hanrath AT, Schim van der Loeff ICD, Barr AS, Sanchez-Gonzalez A, Bergamaschi L, Mescia F, Barnes JL, Kilich E, de Wilton A, Saigal A, Saleh A, Janes SM, Smith CM, Gopee N, Wilson C, Coupland P, Coxhead JM, Kiselev VY, van Dongen S, Bacardit J, King HW; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID-19 BioResource Collaboration; Rostron AJ, Simpson AJ, Hambleton S, Laurenti E, Lyons PA, Meyer KB, Nikolić MZ, Duncan CJA, Smith KGC, Teichmann SA, Clatworthy MR, Marioni JC, Göttgens B, Haniffa M. Stephenson E, et al. Nat Med. 2021 May;27(5):904-916. doi: 10.1038/s41591-021-01329-2. Epub 2021 Apr 20. Nat Med. 2021. PMID: 33879890 Free PMC article.
Early, uncommitted CD34(+) hematopoietic stem/progenitor cells were primed toward megakaryopoiesis, accompanied by expanded megakaryocyte-committed progenitors and increased platelet activation. ...
Early, uncommitted CD34(+) hematopoietic stem/progenitor cells were primed toward megakaryopoiesis, accompanied by expanded megakaryo …
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.
Rodriguez-Meira A, Norfo R, Wen S, Chédeville AL, Rahman H, O'Sullivan J, Wang G, Louka E, Kretzschmar WW, Paterson A, Brierley C, Martin JE, Demeule C, Bashton M, Sousos N, Moralli D, Subha Meem L, Carrelha J, Wu B, Hamblin A, Guermouche H, Pasquier F, Marzac C, Girodon F, Vainchenker W, Drummond M, Harrison C, Chapman JR, Plo I, Jacobsen SEW, Psaila B, Thongjuea S, Antony-Debré I, Mead AJ. Rodriguez-Meira A, et al. Among authors: martin je. Nat Genet. 2023 Sep;55(9):1531-1541. doi: 10.1038/s41588-023-01480-1. Epub 2023 Sep 4. Nat Genet. 2023. PMID: 37666991 Free PMC article.
Understanding the genetic and nongenetic determinants of tumor protein 53 (TP53)-mutation-driven clonal evolution and subsequent transformation is a crucial step toward the design of rational therapeutic strategies. Here we carry out allelic resolution single-cell multi-om …
Understanding the genetic and nongenetic determinants of tumor protein 53 (TP53)-mutation-driven clonal evolution and subsequent transformat …
Abiraterone in metastatic prostate cancer without previous chemotherapy.
Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, de Souza P, Fizazi K, Mainwaring P, Piulats JM, Ng S, Carles J, Mulders PF, Basch E, Small EJ, Saad F, Schrijvers D, Van Poppel H, Mukherjee SD, Suttmann H, Gerritsen WR, Flaig TW, George DJ, Yu EY, Efstathiou E, Pantuck A, Winquist E, Higano CS, Taplin ME, Park Y, Kheoh T, Griffin T, Scher HI, Rathkopf DE; COU-AA-302 Investigators. Ryan CJ, et al. N Engl J Med. 2013 Jan 10;368(2):138-48. doi: 10.1056/NEJMoa1209096. Epub 2012 Dec 10. N Engl J Med. 2013. PMID: 23228172 Free PMC article. Clinical Trial.
CONCLUSIONS: Abiraterone improved radiographic progression-free survival, showed a trend toward improved overall survival, and significantly delayed clinical decline and initiation of chemotherapy in patients with metastatic castration-resistant prostate cancer. ...
CONCLUSIONS: Abiraterone improved radiographic progression-free survival, showed a trend toward improved overall survival, and signif …
Single-Cell RNA-Seq of Mouse Olfactory Bulb Reveals Cellular Heterogeneity and Activity-Dependent Molecular Census of Adult-Born Neurons.
Tepe B, Hill MC, Pekarek BT, Hunt PJ, Martin TJ, Martin JF, Arenkiel BR. Tepe B, et al. Among authors: martin jf. Cell Rep. 2018 Dec 4;25(10):2689-2703.e3. doi: 10.1016/j.celrep.2018.11.034. Cell Rep. 2018. PMID: 30517858 Free PMC article.
Cellular heterogeneity within the mammalian brain poses a challenge toward understanding its complex functions. Within the olfactory bulb, odor information is processed by subtypes of inhibitory interneurons whose heterogeneity and functionality are influenced by ongoing a …
Cellular heterogeneity within the mammalian brain poses a challenge toward understanding its complex functions. Within the olfactory …
Teaching technical surgery.
Huffman EM, Martin JR, Stefanidis D. Huffman EM, et al. Among authors: martin jr. Surgery. 2020 May;167(5):782-786. doi: 10.1016/j.surg.2019.05.026. Epub 2019 Jul 8. Surgery. 2020. PMID: 31296431
Surgical educators face many challenges on the path toward ensuring surgical trainee technical-skill acquisition. We present effective intraoperative teaching techniques and discuss the utilization of simulation to improve technical skills outside of the operating room. .. …
Surgical educators face many challenges on the path toward ensuring surgical trainee technical-skill acquisition. We present effectiv …
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries.
National Institute for Health and Care Research Global Health Research Unit on Global Surgery. National Institute for Health and Care Research Global Health Research Unit on Global Surgery. Br J Surg. 2023 Jun 12;110(7):804-817. doi: 10.1093/bjs/znad092. Br J Surg. 2023. PMID: 37079880 Free PMC article.
In phase 4, the top three shortlisted interventions for low-middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. CONCLUSION: This is a step toward environmentally sustainable operatin …
In phase 4, the top three shortlisted interventions for low-middle-income countries were: introducing reusable surgical devices; reducing us …
Cardiomyocyte Proliferation for Therapeutic Regeneration.
Leach JP, Martin JF. Leach JP, et al. Among authors: martin jf. Curr Cardiol Rep. 2018 Jun 14;20(8):63. doi: 10.1007/s11886-018-1011-x. Curr Cardiol Rep. 2018. PMID: 29904823 Review.
With recent advancements in cardiac regenerative approaches, the induction of endogenous mature cardiomyocyte proliferation has emerged as a new possibility. Here, we review progress made toward the regeneration of cardiac tissue in the mammalian heart through the stimulat …
With recent advancements in cardiac regenerative approaches, the induction of endogenous mature cardiomyocyte proliferation has emerged as a …
Determinants of Cardiac Growth and Size.
Heallen TR, Kadow ZA, Wang J, Martin JF. Heallen TR, et al. Among authors: martin jf. Cold Spring Harb Perspect Biol. 2020 Mar 2;12(3):a037150. doi: 10.1101/cshperspect.a037150. Cold Spring Harb Perspect Biol. 2020. PMID: 31615785 Free PMC article. Review.
Recently, studies performed to understand the regulation of organ size have revealed that both cellular signals and external cues contribute toward the determination of total cell mass within each organ. The establishment of final organ size requires the precise coordinati …
Recently, studies performed to understand the regulation of organ size have revealed that both cellular signals and external cues contribute …
BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology.
Bigenwald C, Le Berichel J, Wilk CM, Chakraborty R, Chen ST, Tabachnikova A, Mancusi R, Abhyankar H, Casanova-Acebes M, Laface I, Akturk G, Jobson J, Karoulia Z, Martin JC, Grout J, Rafiei A, Lin H, Manz MG, Baccarini A, Poulikakos PI, Brown BD, Gnjatic S, Lujambio A, McClain KL, Picarsic J, Allen CE, Merad M. Bigenwald C, et al. Among authors: martin jc. Nat Med. 2021 May;27(5):851-861. doi: 10.1038/s41591-021-01304-x. Epub 2021 May 6. Nat Med. 2021. PMID: 33958797 Free PMC article.
Here we show that enforced expression of the BRAF(V600E) mutation in early mouse and human multipotent HPCs induced a senescence program that led to HPC growth arrest, apoptosis resistance and a senescence-associated secretory phenotype (SASP). SASP, in turn, promoted HPC skewing …
Here we show that enforced expression of the BRAF(V600E) mutation in early mouse and human multipotent HPCs induced a senescence program tha …
New horizons in human sperm selection for assisted reproduction.
Nixon B, Schjenken JE, Burke ND, Skerrett-Byrne DA, Hart HM, De Iuliis GN, Martin JH, Lord T, Bromfield EG. Nixon B, et al. Among authors: martin jh. Front Endocrinol (Lausanne). 2023 Feb 22;14:1145533. doi: 10.3389/fendo.2023.1145533. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36909306 Free PMC article. Review.
In this review, we reflect on recent advances in our mechanistic understanding of sperm biology and function, which are contributing to a growing armory of innovative approaches to diagnose and treat male infertility. In particular we review progress toward the implementat …
In this review, we reflect on recent advances in our mechanistic understanding of sperm biology and function, which are contributing to a gr …
266 results