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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 1
2010 1
2012 1
2014 3
2015 3
2016 1
2017 1
2018 3
2019 3
2020 1
2021 3
2022 1
2024 0

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18 results

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Page 1
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
Wilman HR, Parisinos CA, Atabaki-Pasdar N, Kelly M, Thomas EL, Neubauer S; IMI DIRECT Consortium; Mahajan A, Hingorani AD, Patel RS, Hemingway H, Franks PW, Bell JD, Banerjee R, Yaghootkar H. Wilman HR, et al. J Hepatol. 2019 Sep;71(3):594-602. doi: 10.1016/j.jhep.2019.05.032. Epub 2019 Jun 19. J Hepatol. 2019. PMID: 31226389 Free PMC article.
Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors.
Martínez-González S, Alvarez RM, Martín JI, García AB, Riesco-Fagundo C, Varela C, Rodríguez Hergueta A, González Cantalapiedra E, Albarrán MI, Gómez-Casero E, Cebriá A, Aguirre E, Ajenjo N, Cebrián D, Di Geronimo B, Cunningham D, O'Neill M, Dave HPG, Blanco-Aparicio C, Pastor J. Martínez-González S, et al. ACS Med Chem Lett. 2021 Nov 2;12(11):1794-1801. doi: 10.1021/acsmedchemlett.1c00412. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795869 Free PMC article.
We report the medicinal chemistry exploration and biological characterization of a series of thieno[3,2-d]pyrimidine MCXs, which led to the discovery of IBL-302 (31), a potent, selective, and orally bioavailable triple PI3K/mTOR/PIM inhibitor. IBL-302, currently in …
We report the medicinal chemistry exploration and biological characterization of a series of thieno[3,2-d]pyrimidine MCXs, which led to the …
A cognitive model of dynamic cooperation with varied interdependency information.
Gonzalez C, Ben-Asher N, Martin JM, Dutt V. Gonzalez C, et al. Cogn Sci. 2015 Apr;39(3):457-95. doi: 10.1111/cogs.12170. Epub 2014 Sep 23. Cogn Sci. 2015. PMID: 25250832 Free article.
We analyze the dynamics of repeated interaction of two players in the Prisoner's Dilemma (PD) under various levels of interdependency information and propose an instance-based learning cognitive model (IBL-PD) to explain how cooperation emerges over time. Six hypotheses ar …
We analyze the dynamics of repeated interaction of two players in the Prisoner's Dilemma (PD) under various levels of interdependency inform …
Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease.
Dhiman K, Gupta VB, Villemagne VL, Eratne D, Graham PL, Fowler C, Bourgeat P, Li QX, Collins S, Bush AI, Rowe CC, Masters CL, Ames D, Hone E, Blennow K, Zetterberg H, Martins RN. Dhiman K, et al. Alzheimers Dement (Amst). 2020 Feb 27;12(1):e12005. doi: 10.1002/dad2.12005. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 32211500 Free PMC article.
Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total knee arthroplasty: results of a randomized controlled trial (TRAC-24).
Magill P, Hill JC, Bryce L, Martin U, Dorman A, Hogg R, Campbell C, Gardner E, McFarland M, Bell J, Benson G, Beverland D. Magill P, et al. Bone Joint J. 2021 Oct;103-B(10):1595-1603. doi: 10.1302/0301-620X.103B10.BJJ-2020-2308.R1. Bone Joint J. 2021. PMID: 34587808 Clinical Trial.
METHODS: TRAC-24 was a prospective, phase IV, single-centre, open label, parallel group, randomized controlled trial on patients undergoing TKA, including those labelled as high-risk. The primary outcome was indirect calculated blood loss (IBL) at 48 hours. Group 1 receive …
METHODS: TRAC-24 was a prospective, phase IV, single-centre, open label, parallel group, randomized controlled trial on patients undergoing …
Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total hip arthroplasty: results of a randomized controlled trial (TRAC-24).
Magill P, Hill JC, Bryce L, Martin U, Dorman A, Hogg R, Campbell C, Gardner E, McFarland M, Bell J, Benson G, Beverland D. Magill P, et al. Bone Joint J. 2021 Jul;103-B(7):1197-1205. doi: 10.1302/0301-620X.103B7.BJJ-2020-2309.R1. Bone Joint J. 2021. PMID: 34192922 Clinical Trial.
The primary outcome measure was the indirect calculated blood loss (IBL) at 48 hours. The patients were randomized into three groups. ...RESULTS: A total of 534 patients were randomized, with 233 in group 1, 235 in group 2, and 66 in group 3; 92 patients (17.2%) were consi …
The primary outcome measure was the indirect calculated blood loss (IBL) at 48 hours. The patients were randomized into three groups. …
18 results