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Chromatin architecture changes and DNA replication fork collapse are critical features in cryopreserved cells that are differentially controlled by cryoprotectants.
Falk M, Falková I, Kopečná O, Bačíková A, Pagáčová E, Šimek D, Golan M, Kozubek S, Pekarová M, Follett SE, Klejdus B, Elliott KW, Varga K, Teplá O, Kratochvílová I. Falk M, et al. Among authors: golan m. Sci Rep. 2018 Oct 2;8(1):14694. doi: 10.1038/s41598-018-32939-5. Sci Rep. 2018. PMID: 30279538 Free PMC article.
Theoretical and experimental study of the antifreeze protein AFP752, trehalose and dimethyl sulfoxide cryoprotection mechanism: correlation with cryopreserved cell viability.
Kratochvílová I, Golan M, Pomeisl K, Richter J, Sedláková S, Šebera J, Mičová J, Falk M, Falková I, Řeha D, Elliott KW, Varga K, Follett SE, Šimek D. Kratochvílová I, et al. Among authors: golan m. RSC Adv. 2017;7(1):352-360. doi: 10.1039/C6RA25095E. Epub 2016 Dec 23. RSC Adv. 2017. PMID: 28936355 Free PMC article.