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Contribution of hyperglycemia-induced changes in microglia to Alzheimer's disease pathology.
Hernández-Rodríguez M, Clemente CF, Macías-Pérez ME, Rodríguez-Fonseca RA, Vázquez MIN, Martínez J, Ruvalcaba RM, Rosas MM, Jiménez EM. Hernández-Rodríguez M, et al. Among authors: macias perez me. Pharmacol Rep. 2022 Oct;74(5):832-846. doi: 10.1007/s43440-022-00405-9. Epub 2022 Aug 31. Pharmacol Rep. 2022. PMID: 36042131 Review.
Cucurbitacin I elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-kinase.
Sari-Hassoun M, Clement MJ, Hamdi I, Bollot G, Bauvais C, Joshi V, Toma F, Burgo A, Cailleret M, Rosales-Hernández MC, Macias Pérez ME, Chabane-Sari D, Curmi PA. Sari-Hassoun M, et al. Among authors: macias perez me. Biochem Pharmacol. 2016 Feb 15;102:45-63. doi: 10.1016/j.bcp.2015.12.013. Epub 2015 Dec 18. Biochem Pharmacol. 2016. PMID: 26707799
In vitro and computational studies showed that perezone inhibits PARP-1 and induces changes in the redox state of K562 cells.
Hernández-Rodríguez M, Mendoza Sánchez PI, Macias Perez ME, Rosales Cruz E, Mera Jiménez E, Nicolás Vázquez MI, Miranda Ruvalcaba R. Hernández-Rodríguez M, et al. Among authors: macias perez me. Arch Biochem Biophys. 2019 Aug 15;671:225-234. doi: 10.1016/j.abb.2019.05.002. Epub 2019 May 4. Arch Biochem Biophys. 2019. PMID: 31063714
Design of Two New Sulfur Derivatives of Perezone: In Silico Study Simulation Targeting PARP-1 and In Vitro Study Validation Using Cancer Cell Lines.
Rubiales-Martínez A, Martínez J, Mera-Jiménez E, Pérez-Flores J, Téllez-Isaías G, Miranda Ruvalcaba R, Hernández-Rodríguez M, Mancilla Percino T, Macías Pérez ME, Nicolás-Vázquez MI. Rubiales-Martínez A, et al. Among authors: macias perez me. Int J Mol Sci. 2024 Jan 10;25(2):868. doi: 10.3390/ijms25020868. Int J Mol Sci. 2024. PMID: 38255943 Free PMC article.