Glycosaminoglycans are important mediators of neutrophilic inflammation in vivo.
Gschwandtner M, Strutzmann E, Teixeira MM, Anders HJ, Diedrichs-Möhring M, Gerlza T, Wildner G, Russo RC, Adage T, Kungl AJ.
Gschwandtner M, et al.
Cytokine. 2017 Mar;91:65-73. doi: 10.1016/j.cyto.2016.12.008. Epub 2016 Dec 21.
Cytokine. 2017.
PMID: 28011398
In this study, we show that neutrophil transmigration in vitro can be reduced by adding soluble GAGs and that this process is specific with respect to the nature of the glycan. To further investigate the GAG influence on neutrophil migration, we have used an engineered CXC …
In this study, we show that neutrophil transmigration in vitro can be reduced by adding soluble GAGs and that this process is specific with …