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Page 1
Fine-tuning the antigen sensitivity of CAR T cells: emerging strategies and current challenges.
Front Immunol. 2023 Nov 27;14:1321596. doi: 10.3389/fimmu.2023.1321596. eCollection 2023.
Front Immunol. 2023.
PMID: 38090558
Free PMC article.
Review.
The growing world of CAR T cell trials: a systematic review.
Holzinger A, Barden M, Abken H.
Holzinger A, et al. Among authors: barden m.
Cancer Immunol Immunother. 2016 Dec;65(12):1433-1450. doi: 10.1007/s00262-016-1895-5. Epub 2016 Sep 9.
Cancer Immunol Immunother. 2016.
PMID: 27613725
Free PMC article.
Review.
Item in Clipboard
CAR Triggered Release of Type-1 Interferon Limits CAR T-Cell Activities by an Artificial Negative Autocrine Loop.
Harrer DC, Schenkel C, Bezler V, Kaljanac M, Hartley J, Barden M, Pan H, Holzinger A, Herr W, Abken H.
Harrer DC, et al. Among authors: barden m.
Cells. 2022 Nov 30;11(23):3839. doi: 10.3390/cells11233839.
Cells. 2022.
PMID: 36497099
Free PMC article.
Item in Clipboard
Magnetic CAR T cell purification using an anti-G4S linker antibody.
Harrer DC, Li SS, Kaljanac M, Bezler V, Barden M, Pan H, Herr W, Abken H.
Harrer DC, et al. Among authors: barden m.
J Immunol Methods. 2024 May;528:113667. doi: 10.1016/j.jim.2024.113667. Epub 2024 Apr 2.
J Immunol Methods. 2024.
PMID: 38574803
Free article.
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IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors.
Hombach A, Barden M, Hannappel L, Chmielewski M, Rappl G, Sachinidis A, Abken H.
Hombach A, et al. Among authors: barden m.
Mol Ther. 2022 Feb 2;30(2):593-605. doi: 10.1016/j.ymthe.2021.10.011. Epub 2021 Oct 19.
Mol Ther. 2022.
PMID: 34678512
Free PMC article.
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CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activation.
Barden M, Holzinger A, Velas L, Mezősi-Csaplár M, Szöőr Á, Vereb G, Schütz GJ, Hombach AA, Abken H.
Barden M, et al.
Front Immunol. 2023 Feb 1;14:1110482. doi: 10.3389/fimmu.2023.1110482. eCollection 2023.
Front Immunol. 2023.
PMID: 36817444
Free PMC article.
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