Mark J. Murphy - Search Results

Year	Number of Results
2004	1
2005	2
2008	2
2009	1
2010	1
2011	1
2012	1
2013	1
2014	1
2020	1
2021	2
2022	2
2023	1
2024	1

1

Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies.

Meyer EA, Äänismaa P, Ertel EA, Hühn E, Strasser DS, Rey M, Murphy MJ, Martinic MM, Pouzol L, Froidevaux S, Keller MP, Caroff E. Meyer EA, et al. Among authors: murphy mj. J Med Chem. 2023 Mar 23;66(6):4179-4196. doi: 10.1021/acs.jmedchem.3c00074. Epub 2023 Mar 8. J Med Chem. 2023. PMID: 36883854

2

The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration.

Baumann M, Lack B, Guillaumat I, Murphy MJ, Riederer MA. Baumann M, et al. Among authors: murphy mj. Platelets. 2022 Jan 2;33(1):147-156. doi: 10.1080/09537104.2020.1869711. Epub 2021 Jan 11. Platelets. 2022. PMID: 33427002

3

Essential role for Pbx1 in corneal morphogenesis.

Murphy MJ, Polok BK, Schorderet DF, Cleary ML. Murphy MJ, et al. Invest Ophthalmol Vis Sci. 2010 Feb;51(2):795-803. doi: 10.1167/iovs.08-3327. Epub 2009 Sep 24. Invest Ophthalmol Vis Sci. 2010. PMID: 19797217 Free PMC article.

4

Cenerimod, a selective S1P₁ receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren's syndrome.

Gerossier E, Nayar S, Froidevaux S, Smith CG, Runser C, Iannizzotto V, Vezzali E, Pierlot G, Mentzel U, Murphy MJ, Martinic MM, Barone F. Gerossier E, et al. Among authors: murphy mj. Arthritis Res Ther. 2021 Nov 29;23(1):289. doi: 10.1186/s13075-021-02673-x. Arthritis Res Ther. 2021. PMID: 34839819 Free PMC article.

5

In Vitro Characterization of Sphingosine 1-Phosphate Receptor 1 (S1P₁) Expression and Mediated Migration of Primary Human T and B Cells in the Context of Cenerimod, a Novel, Selective S1P₁ Receptor Modulator.

Schlicher L, Kulig P, von Münchow A, Murphy MJ, Keller MP. Schlicher L, et al. Among authors: murphy mj. Int J Mol Sci. 2022 Jan 21;23(3):1191. doi: 10.3390/ijms23031191. Int J Mol Sci. 2022. PMID: 35163112 Free PMC article.

6

Discovery and Characterization of a New Class of C5aR1 Antagonists Showing In Vivo Activity.

Hubler F, Renneberg D, Siendt H, Stamm S, Hilpert K, Caroff E, Delahaye S, Froidevaux S, Murphy MJ. Hubler F, et al. Among authors: murphy mj. J Med Chem. 2024 Mar 14;67(5):4100-4119. doi: 10.1021/acs.jmedchem.3c02375. Epub 2024 Mar 4. J Med Chem. 2024. PMID: 38482828

7

MLL becomes functional through intra-molecular interaction not by proteolytic processing.

Yokoyama A, Ficara F, Murphy MJ, Meisel C, Hatanaka C, Kitabayashi I, Cleary ML. Yokoyama A, et al. Among authors: murphy mj. PLoS One. 2013 Sep 10;8(9):e73649. doi: 10.1371/journal.pone.0073649. eCollection 2013. PLoS One. 2013. PMID: 24040009 Free PMC article.

8

Preclinical to clinical translation of cenerimod, a novel S1P₁ receptor modulator, in systemic lupus erythematosus.

Strasser DS, Froidevaux S, Sippel V, Gerossier E, Grieder U, Pierlot GM, Kieninger-Graefitsch A, Vezzali E, Stalder AK, Renault B, Ryge J, Hart A, Mentzel U, Groenen PMA, Keller MP, Trendelenburg M, Martinic MM, Murphy MJ. Strasser DS, et al. Among authors: murphy mj. RMD Open. 2020 Sep;6(2):e001261. doi: 10.1136/rmdopen-2020-001261. RMD Open. 2020. PMID: 32917831 Free PMC article.

9

ESPIRiT--an eigenvalue approach to autocalibrating parallel MRI: where SENSE meets GRAPPA.

Uecker M, Lai P, Murphy MJ, Virtue P, Elad M, Pauly JM, Vasanawala SS, Lustig M. Uecker M, et al. Among authors: murphy mj. Magn Reson Med. 2014 Mar;71(3):990-1001. doi: 10.1002/mrm.24751. Magn Reson Med. 2014. PMID: 23649942 Free PMC article.

10

More than just proliferation: Myc function in stem cells.

Murphy MJ, Wilson A, Trumpp A. Murphy MJ, et al. Trends Cell Biol. 2005 Mar;15(3):128-37. doi: 10.1016/j.tcb.2005.01.008. Trends Cell Biol. 2005. PMID: 15752976

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