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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 2
2004 7
2005 4
2006 4
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2008 8
2009 11
2010 12
2011 10
2012 7
2013 11
2014 11
2015 20
2016 12
2017 15
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2020 22
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2022 17
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2024 8

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228 results

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Page 1
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA. Mills EL, et al. Among authors: hughes mm. Nature. 2018 Apr 5;556(7699):113-117. doi: 10.1038/nature25986. Epub 2018 Mar 28. Nature. 2018. PMID: 29590092 Free PMC article.
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
Hooftman A, Angiari S, Hester S, Corcoran SE, Runtsch MC, Ling C, Ruzek MC, Slivka PF, McGettrick AF, Banahan K, Hughes MM, Irvine AD, Fischer R, O'Neill LAJ. Hooftman A, et al. Among authors: hughes mm. Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016. Epub 2020 Aug 12. Cell Metab. 2020. PMID: 32791101 Free PMC article.
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target.
Vande Voorde J, Steven RT, Najumudeen AK, Ford CA, Dexter A, Gonzalez-Fernandez A, Nikula CJ, Xiang Y, Ford L, Maneta Stavrakaki S, Gilroy K, Zeiger LB, Pennel K, Hatthakarnkul P, Elia EA, Nasif A, Murta T, Manoli E, Mason S, Gillespie M, Lannagan TRM, Vlahov N, Ridgway RA, Nixon C, Raven A, Mills M, Athineos D, Kanellos G, Nourse C, Gay DM, Hughes M, Burton A, Yan B, Sellers K, Wu V, De Ridder K, Shokry E, Huerta Uribe A, Clark W, Clark G, Kirschner K, Thienpont B, Li VSW, Maddocks ODK, Barry ST, Goodwin RJA, Kinross J, Edwards J, Yuneva MO, Sumpton D, Takats Z, Campbell AD, Bunch J, Sansom OJ. Vande Voorde J, et al. Among authors: hughes m. Nat Metab. 2023 Aug;5(8):1303-1318. doi: 10.1038/s42255-023-00857-0. Epub 2023 Aug 14. Nat Metab. 2023. PMID: 37580540 Free PMC article.
Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial.
Munné S, Kaplan B, Frattarelli JL, Child T, Nakhuda G, Shamma FN, Silverberg K, Kalista T, Handyside AH, Katz-Jaffe M, Wells D, Gordon T, Stock-Myer S, Willman S; STAR Study Group. Munné S, et al. Fertil Steril. 2019 Dec;112(6):1071-1079.e7. doi: 10.1016/j.fertnstert.2019.07.1346. Epub 2019 Sep 21. Fertil Steril. 2019. PMID: 31551155 Free article. Clinical Trial.
Metabolic regulation of NLRP3.
Hughes MM, O'Neill LAJ. Hughes MM, et al. Immunol Rev. 2018 Jan;281(1):88-98. doi: 10.1111/imr.12608. Immunol Rev. 2018. PMID: 29247992 Review.
Glasgow Neuro Society 2021 Conference Proceedings.
Ashraf M, Ismahel H, Lub S, Middleton E, Chaudhary A, Gardee A, Salloum LA, Szilagyi-Nagy E, Wales R, Omar S, Baird TA, O'Kane R; Glasgow Neuro Society conference proceedings presenters’; Holden J, Abdelsadg M, Burr P, Decruz AB, Badran K, Amato-Watkins A, Alakandy L, Boardman R, Nicely L, Tandon V, Banerjee S, Keenlyside A, Hughes M, Ho JW, Sieradzki J, Phan EPM, MacDougall NJJ, Bashir ABBA, Hutton DL, Doley ASF, Oochit KK, Kontorinis G, Wong YY. Ashraf M, et al. Among authors: hughes m. Surg Neurol Int. 2022 Apr 29;13:173. doi: 10.25259/SNI_268_2022. eCollection 2022. Surg Neurol Int. 2022. PMID: 35509535 Free PMC article. No abstract available.
Promoting equity and inclusion.
Hughes M. Hughes M. Australas J Ageing. 2023 Jun;42(2):271-272. doi: 10.1111/ajag.13221. Australas J Ageing. 2023. PMID: 37354006 No abstract available.
Insinuating electronics in the brain.
Hughes MA. Hughes MA. Surgeon. 2016 Aug;14(4):213-8. doi: 10.1016/j.surge.2016.03.003. Epub 2016 Apr 9. Surgeon. 2016. PMID: 27072790 Free PMC article. Review.
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.
Leach JDG, Vlahov N, Tsantoulis P, Ridgway RA, Flanagan DJ, Gilroy K, Sphyris N, Vázquez EG, Vincent DF, Faller WJ, Hodder MC, Raven A, Fey S, Najumudeen AK, Strathdee D, Nixon C, Hughes M, Clark W, Shaw R; S:CORT consortium; van Hooff SR, Huels DJ, Medema JP, Barry ST, Frame MC, Unciti-Broceta A, Leedham SJ, Inman GJ, Jackstadt R, Thompson BJ, Campbell AD, Tejpar S, Sansom OJ. Leach JDG, et al. Among authors: hughes m. Nat Commun. 2021 Jun 8;12(1):3464. doi: 10.1038/s41467-021-23717-5. Nat Commun. 2021. PMID: 34103493 Free PMC article.
Disabling iatrogenic disorder.
Hughes M, Wijeyekoon B. Hughes M, et al. BMJ Case Rep. 2016 Jun 16;2016:bcr2016214807. doi: 10.1136/bcr-2016-214807. BMJ Case Rep. 2016. PMID: 27312853 Free PMC article. No abstract available.
228 results