Marina T. Varela - Search Results

Year	Number of Results
2016	1
2017	2
2018	2
2019	1
2020	6
2021	2
2022	2
2023	4
2024	0

1

Natural Products: Key Prototypes to Drug Discovery Against Neglected Diseases Caused by Trypanosomatids.

Varela MT, Fernandes JPS. Varela MT, et al. Curr Med Chem. 2020;27(13):2133-2146. doi: 10.2174/0929867325666180501102450. Curr Med Chem. 2020. PMID: 29714138 Review.

2

Pyrazinoates as antiparasitic agents against Trypanosoma cruzi.

Vasconcelos CI, Varela MT, Torrecilhas AC, Fernandes JPS. Vasconcelos CI, et al. Among authors: varela mt. Arch Pharm (Weinheim). 2018 Nov;351(11):e1800190. doi: 10.1002/ardp.201800190. Epub 2018 Oct 9. Arch Pharm (Weinheim). 2018. PMID: 30298951

3

Bioisosteric modification on benzylidene-carbonyl compounds improved the drug-likeness and maintained the antifungal activity against Sporothrix brasiliensis.

Waller SB, Cleff MB, Ripoll MK, Meireles MCA, Ferrarini M, Varela MT, Fernandes JPS. Waller SB, et al. Chem Biol Drug Des. 2022 Mar;99(3):391-397. doi: 10.1111/cbdd.13994. Epub 2021 Dec 12. Chem Biol Drug Des. 2022. PMID: 34873847

4

Benzylidene-carbonyl compounds are active against itraconazole-susceptible and itraconazole-resistant Sporothrix brasiliensis.

Waller SB, Cleff MB, Ripoll MK, Meireles MCA, Varela MT, Fernandes JPDS. Waller SB, et al. Folia Microbiol (Praha). 2020 Dec;65(6):1033-1038. doi: 10.1007/s12223-020-00814-4. Epub 2020 Aug 21. Folia Microbiol (Praha). 2020. PMID: 32821987

5

Esterification of p-Coumaric Acid Improves the Control over Melanoma Cell Growth.

Carmo-Martins JI, Gonzatti MB, Varela MT, Sousa MEP, Costa LVS, Rodrigues EG, Fernandes JPS, Keller AC. Carmo-Martins JI, et al. Among authors: varela mt. Biomedicines. 2023 Jan 12;11(1):196. doi: 10.3390/biomedicines11010196. Biomedicines. 2023. PMID: 36672704 Free PMC article.

6

Investigation of Structure-Activity Relationships for Benzoyl and Cinnamoyl Piperazine/Piperidine Amides as Tyrosinase Inhibitors.

Varela MT, de Castro Levatti EV, Tempone AG, Fernandes JPS. Varela MT, et al. ACS Omega. 2023 Nov 9;8(46):44265-44275. doi: 10.1021/acsomega.3c06977. eCollection 2023 Nov 21. ACS Omega. 2023. PMID: 38027351 Free PMC article.

7

Synthetic Analogues of Gibbilimbol B Induce Bioenergetic Damage and Calcium Imbalance in Trypanosoma cruzi.

Amaral M, Varela MT, Kant R, Christodoulides M, Fernandes JPS, Tempone AG. Amaral M, et al. Among authors: varela mt. Life (Basel). 2023 Feb 28;13(3):663. doi: 10.3390/life13030663. Life (Basel). 2023. PMID: 36983820 Free PMC article.

8

Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi.

Varela MT, Amaral M, Romanelli MM, de Castro Levatti EV, Tempone AG, Fernandes JPS. Varela MT, et al. Eur J Pharm Sci. 2022 Apr 1;171:106114. doi: 10.1016/j.ejps.2021.106114. Epub 2022 Jan 2. Eur J Pharm Sci. 2022. PMID: 34986415 Free article.

9

Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands - Functional characterization and modeling studies on H₃ and H₄ receptors.

Corrêa MF, Balico-Silva AL, Kiss DJ, Fernandes GAB, Maraschin JC, Parreiras-E-Silva LT, Varela MT, Simões SC, Bouvier M, Keserű GM, Costa-Neto CM, Fernandes JPS. Corrêa MF, et al. Among authors: varela mt. Bioorg Med Chem. 2021 Jan 15;30:115924. doi: 10.1016/j.bmc.2020.115924. Epub 2020 Dec 8. Bioorg Med Chem. 2021. PMID: 33333448

10

Coumaric acid derivatives as tyrosinase inhibitors: Efficacy studies through in silico, in vitro and ex vivo approaches.

Varela MT, Ferrarini M, Mercaldi VG, Sufi BDS, Padovani G, Nazato LIS, Fernandes JPS. Varela MT, et al. Bioorg Chem. 2020 Oct;103:104108. doi: 10.1016/j.bioorg.2020.104108. Epub 2020 Jul 21. Bioorg Chem. 2020. PMID: 32750608

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