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Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina.
Tornabene P, Trapani I, Minopoli R, Centrulo M, Lupo M, de Simone S, Tiberi P, Dell'Aquila F, Marrocco E, Iodice C, Iuliano A, Gesualdo C, Rossi S, Giaquinto L, Albert S, Hoyng CB, Polishchuk E, Cremers FPM, Surace EM, Simonelli F, De Matteis MA, Polishchuk R, Auricchio A. Tornabene P, et al. Among authors: lupo m. Sci Transl Med. 2019 May 15;11(492):eaav4523. doi: 10.1126/scitranslmed.aav4523. Sci Transl Med. 2019. PMID: 31092694 Free PMC article.
Medical Device Development for Children and Young People-Reviewing the Challenges and Opportunities.
Dimitri P, Pignataro V, Lupo M, Bonifazi D, Henke M, Musazzi UM, Ernst F, Minghetti P, Redaelli DF, Antimisiaris SG, Migliaccio G, Bonifazi F, Marciani L, Courtenay AJ, Denora N, Lopedota A. Dimitri P, et al. Among authors: lupo m. Pharmaceutics. 2021 Dec 17;13(12):2178. doi: 10.3390/pharmaceutics13122178. Pharmaceutics. 2021. PMID: 34959459 Free PMC article. Review.
Rhodopsin targeted transcriptional silencing by DNA-binding.
Botta S, Marrocco E, de Prisco N, Curion F, Renda M, Sofia M, Lupo M, Carissimo A, Bacci ML, Gesualdo C, Rossi S, Simonelli F, Surace EM. Botta S, et al. Among authors: lupo m. Elife. 2016 Mar 14;5:e12242. doi: 10.7554/eLife.12242. Elife. 2016. PMID: 26974343 Free PMC article.
Paediatric clinical research in Europe: an insight on experts' needs and perspectives.
Ruggieri L, Ceci A, Bartoloni F, Elie V, Felisi M, Jacqz-Aigrain E, Lupo M, Malik S, Manfredi C, Reggiardo G, Demotes J, Bonifazi D. Ruggieri L, et al. Among authors: lupo m. Contemp Clin Trials Commun. 2021 Feb 10;21:100735. doi: 10.1016/j.conctc.2021.100735. eCollection 2021 Mar. Contemp Clin Trials Commun. 2021. PMID: 33665471 Free PMC article.
Inclusion of a degron reduces levelsof undesired inteins after AAV-mediated proteintrans-splicing in the retina.
Tornabene P, Trapani I, Centrulo M, Marrocco E, Minopoli R, Lupo M, Iodice C, Gesualdo C, Simonelli F, Surace EM, Auricchio A. Tornabene P, et al. Among authors: lupo m. Mol Ther Methods Clin Dev. 2021 Oct 19;23:448-459. doi: 10.1016/j.omtm.2021.10.004. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34786437 Free PMC article.
Children's Preferences for Oral Dosage Forms and Their Involvement in Formulation Research via EPTRI (European Paediatric Translational Research Infrastructure).
Alessandrini E, Brako F, Scarpa M, Lupo M, Bonifazi D, Pignataro V, Cavallo M, Cullufe O, Enache C, Nafria B, Claverol J, De Taeye L, Vermeulen E, Preston J, Tuleu C. Alessandrini E, et al. Among authors: lupo m. Pharmaceutics. 2021 May 15;13(5):730. doi: 10.3390/pharmaceutics13050730. Pharmaceutics. 2021. PMID: 34063499 Free PMC article.