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Isoform-selective HDAC1/6/8 inhibitors with an imidazo-ketopiperazine cap containing stereochemical diversity.
Lecointre B, Narozny R, Borrello MT, Senger J, Chakrabarti A, Jung M, Marek M, Romier C, Melesina J, Sippl W, Bischoff L, Ganesan A. Lecointre B, et al. Among authors: borrello mt. Philos Trans R Soc Lond B Biol Sci. 2018 Jun 5;373(1748):20170364. doi: 10.1098/rstb.2017.0364. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29685969 Free PMC article.
cis-Cyclopropylamines as mechanism-based inhibitors of monoamine oxidases.
Malcomson T, Yelekci K, Borrello MT, Ganesan A, Semina E, De Kimpe N, Mangelinckx S, Ramsay RR. Malcomson T, et al. Among authors: borrello mt. FEBS J. 2015 Aug;282(16):3190-8. doi: 10.1111/febs.13260. Epub 2015 Mar 27. FEBS J. 2015. PMID: 25755053 Free article.
Efficient synthesis and biological evaluation of proximicins A, B and C.
Brucoli F, Natoli A, Marimuthu P, Borrello MT, Stapleton P, Gibbons S, Schätzlein A. Brucoli F, et al. Among authors: borrello mt. Bioorg Med Chem. 2012 Mar 15;20(6):2019-24. doi: 10.1016/j.bmc.2012.01.043. Epub 2012 Feb 4. Bioorg Med Chem. 2012. PMID: 22364744
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