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Interferon-γ drives macrophage reprogramming, cerebrovascular remodelling, and cognitive dysfunction in a zebrafish and a mouse model of ion imbalance and pressure overload.
Apaydin DC, Zakarauskas-Seth BI, Carnevale L, Apaydin O, Perrotta M, Carnevale R, Kotini MP, Kotlar-Goldaper I, Belting HG, Carnevale D, Filosa A, Sawamiphak S. Apaydin DC, et al. Among authors: kotini mp. Cardiovasc Res. 2023 May 22;119(5):1234-1249. doi: 10.1093/cvr/cvac188. Cardiovasc Res. 2023. PMID: 36536484
Vinculin strengthens the endothelial barrier during vascular development.
van der Stoel MM, Kotini MP, Schoon RM, Affolter M, Belting HG, Huveneers S. van der Stoel MM, et al. Among authors: kotini mp. Vasc Biol. 2023 Jan 27;5(1):e220012. doi: 10.1530/VB-22-0012. Print 2023 Jan 1. Vasc Biol. 2023. PMID: 36260739 Free PMC article.
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte A, Casado P, Castillo SD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, Affolter M, Gerhardt H, Huveneers S, Belting HG, Cutillas PR, Graupera M. Angulo-Urarte A, et al. Nat Commun. 2018 Nov 16;9(1):4826. doi: 10.1038/s41467-018-07172-3. Nat Commun. 2018. PMID: 30446640 Free PMC article.