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Exome sequencing in patient-parent trios suggests new candidate genes for early-onset primary sclerosing cholangitis.
Haisma SM, Weersma RK, Joosse ME, de Koning BAE, de Meij T, Koot BGP, Wolters V, Norbruis O, Daly MJ, Stevens C, Xavier RJ, Koskela J, Rivas MA, Visschedijk MC, Verkade HJ, Barbieri R, Jansen DBH, Festen EAM, van Rheenen PF, van Diemen CC. Haisma SM, et al. Among authors: joosse me. Liver Int. 2021 May;41(5):1044-1057. doi: 10.1111/liv.14831. Epub 2021 Mar 11. Liver Int. 2021. PMID: 33590606 Free PMC article.
Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis.
Joosse ME, Charbit-Henrion F, Boisgard R, Raatgeep RHC, Lindenbergh-Kortleve DJ, Costes LMM, Nugteren S, Guegan N, Parlato M, Veenbergen S, Malan V, Nowak JK, Hollink IHIM, Mearin ML, Escher JC, Cerf-Bensussan N, Samsom JN. Joosse ME, et al. Mucosal Immunol. 2021 Sep;14(5):1172-1182. doi: 10.1038/s41385-021-00423-5. Epub 2021 Jul 5. Mucosal Immunol. 2021. PMID: 34226674 Free PMC article.
Frequencies of circulating regulatory TIGIT+CD38+ effector T cells correlate with the course of inflammatory bowel disease.
Joosse ME, Menckeberg CL, de Ruiter LF, Raatgeep HRC, van Berkel LA, Simons-Oosterhuis Y, Tindemans I, Muskens AFM, Hendriks RW, Hoogenboezem RM, Cupedo T, de Ridder L, Escher JC, Veenbergen S, Samsom JN. Joosse ME, et al. Mucosal Immunol. 2019 Jan;12(1):154-163. doi: 10.1038/s41385-018-0078-4. Epub 2018 Aug 20. Mucosal Immunol. 2019. PMID: 30127383 Free article.
12 results