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From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia.
Astolfi A, Milano F, Palazzotti D, Brea J, Pismataro MC, Morlando M, Tabarrini O, Loza MI, Massari S, Martelli MP, Barreca ML. Astolfi A, et al. Among authors: pismataro mc. Pharmaceutics. 2022 Oct 26;14(11):2295. doi: 10.3390/pharmaceutics14112295. Pharmaceutics. 2022. PMID: 36365115 Free PMC article.
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines.
Pacetti M, Pismataro MC, Felicetti T, Giammarino F, Bonomini A, Tiecco M, Bertagnin C, Barreca ML, Germani R, Cecchetti V, Vicenti I, Tabarrini O, Zazzi M, Loregian A, Massari S. Pacetti M, et al. Among authors: pismataro mc. Org Biomol Chem. 2024 Jan 24;22(4):767-783. doi: 10.1039/d3ob01861j. Org Biomol Chem. 2024. PMID: 38167738
Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase.
Massari S, Bertagnin C, Pismataro MC, Donnadio A, Nannetti G, Felicetti T, Di Bona S, Nizi MG, Tensi L, Manfroni G, Loza MI, Sabatini S, Cecchetti V, Brea J, Goracci L, Loregian A, Tabarrini O. Massari S, et al. Among authors: pismataro mc. Eur J Med Chem. 2021 Jan 1;209:112944. doi: 10.1016/j.ejmech.2020.112944. Epub 2020 Oct 16. Eur J Med Chem. 2021. PMID: 33328103 Free PMC article.
Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation.
Quadri M, Matera C, Silnović A, Pismataro MC, Horenstein NA, Stokes C, Papke RL, Dallanoce C. Quadri M, et al. Among authors: pismataro mc. ChemMedChem. 2017 Aug 22;12(16):1335-1348. doi: 10.1002/cmdc.201700162. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28494140 Free PMC article.