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Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells.
Lustig M, Chan C, Jansen JHM, Bräutigam M, Kölling MA, Gehlert CL, Baumann N, Mester S, Foss S, Andersen JT, Bastian L, Sondermann P, Peipp M, Burger R, Leusen JHW, Valerius T. Lustig M, et al. Among authors: brautigam m. Front Immunol. 2023 Jun 6;14:1178817. doi: 10.3389/fimmu.2023.1178817. eCollection 2023. Front Immunol. 2023. PMID: 37346044 Free PMC article.
A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae.
Kaplonek P, Yao L, Reppe K, Voß F, Kohler T, Ebner F, Schäfer A, Blohm U, Priegue P, Bräutigam M, Pereira CL, Parameswarappa SG, Emmadi M, Ménová P, Witzenrath M, Hammerschmidt S, Hartmann S, Sander LE, Seeberger PH. Kaplonek P, et al. Among authors: brautigam m. Vaccine. 2022 Feb 11;40(7):1038-1046. doi: 10.1016/j.vaccine.2021.12.068. Epub 2022 Jan 13. Vaccine. 2022. PMID: 35033388
A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN.
Wawrzinek R, Wamhoff EC, Lefebre J, Rentzsch M, Bachem G, Domeniconi G, Schulze J, Fuchsberger FF, Zhang H, Modenutti C, Schnirch L, Marti MA, Schwardt O, Bräutigam M, Guberman M, Hauck D, Seeberger PH, Seitz O, Titz A, Ernst B, Rademacher C. Wawrzinek R, et al. Among authors: brautigam m. J Am Chem Soc. 2021 Nov 17;143(45):18977-18988. doi: 10.1021/jacs.1c07235. Epub 2021 Nov 8. J Am Chem Soc. 2021. PMID: 34748320 Free PMC article.