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Page 1
Diffusing Alpha-Emitters Radiation Therapy Promotes a Proimmunogenic Tumor Microenvironment and Synergizes With Programmed Cell Death Protein 1 Blockade.
Mare SD, Nishri Y, Shai A, Efrati M, Deutsch L, Den RB, Kelson I, Keisari Y, Domankevich V. Mare SD, et al. Among authors: efrati m. Int J Radiat Oncol Biol Phys. 2023 Mar 1;115(3):707-718. doi: 10.1016/j.ijrobp.2022.08.043. Epub 2022 Aug 27. Int J Radiat Oncol Biol Phys. 2023. PMID: 36031029 Free article.
Combining alpha radiation-based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor-specific long-term immune response.
Domankevich V, Cohen A, Efrati M, Schmidt M, Rammensee HG, Nair SS, Tewari A, Kelson I, Keisari Y. Domankevich V, et al. Among authors: efrati m. Cancer Immunol Immunother. 2019 Dec;68(12):1949-1958. doi: 10.1007/s00262-019-02418-5. Epub 2019 Oct 22. Cancer Immunol Immunother. 2019. PMID: 31637474 Free PMC article.
RIG-1-Like Receptor Activation Synergizes With Intratumoral Alpha Radiation to Induce Pancreatic Tumor Rejection, Triple-Negative Breast Metastases Clearance, and Antitumor Immune Memory in Mice.
Domankevich V, Efrati M, Schmidt M, Glikson E, Mansour F, Shai A, Cohen A, Zilberstein Y, Flaisher E, Galalae R, Kelson I, Keisari Y. Domankevich V, et al. Among authors: efrati m. Front Oncol. 2020 Jul 17;10:990. doi: 10.3389/fonc.2020.00990. eCollection 2020. Front Oncol. 2020. PMID: 32766128 Free PMC article.
Ablation of experimental colon cancer by intratumoral 224Radium-loaded wires is mediated by alpha particles released from atoms which spread in the tumor and can be augmented by chemotherapy.
Reitkopf-Brodutch S, Confino H, Schmidt M, Cooks T, Efrati M, Arazi L, Rath-Wolfson L, Marshak G, Kelson I, Keisari Y. Reitkopf-Brodutch S, et al. Among authors: efrati m. Int J Radiat Biol. 2015 Feb;91(2):179-86. doi: 10.3109/09553002.2015.959666. Epub 2015 Jan 29. Int J Radiat Biol. 2015. PMID: 25179346