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Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease.
Zaręba P, Łątka K, Mazur G, Gryzło B, Pasieka A, Godyń J, Panek D, Skrzypczak-Wiercioch A, Höfner GC, Latacz G, Maj M, Espargaró A, Sabaté R, Jóźwiak K, Wanner KT, Sałat K, Malawska B, Kulig K, Bajda M. Zaręba P, et al. Eur J Med Chem. 2023 Dec 5;261:115832. doi: 10.1016/j.ejmech.2023.115832. Epub 2023 Oct 7. Eur J Med Chem. 2023. PMID: 37837674 Free article.
Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
Godyń J, Zaręba P, Łażewska D, Stary D, Reiner-Link D, Frank A, Latacz G, Mogilski S, Kaleta M, Doroz-Płonka A, Lubelska A, Honkisz-Orzechowska E, Olejarz-Maciej A, Handzlik J, Stark H, Kieć-Kononowicz K, Malawska B, Bajda M. Godyń J, et al. Bioorg Chem. 2021 Sep;114:105129. doi: 10.1016/j.bioorg.2021.105129. Epub 2021 Jun 28. Bioorg Chem. 2021. PMID: 34217977 Free article.
Neuroimaging of chronotype, sleep quality and daytime sleepiness: Structural T1-weighted magnetic resonance brain imaging data from 136 young adults.
Zareba MR, Fafrowicz M, Marek T, Beldzik E, Oginska H, Beres A, Faba P, Janik J, Lewandowska K, Ostrogorska M, Sikora-Wachowicz B, Zyrkowska A, Domagalik A. Zareba MR, et al. Data Brief. 2022 Feb 15;41:107956. doi: 10.1016/j.dib.2022.107956. eCollection 2022 Apr. Data Brief. 2022. PMID: 35242936 Free PMC article.
Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives.
Jończyk J, Lodarski K, Staszewski M, Godyń J, Zaręba P, Soukup O, Janockova J, Korabecny J, Sałat K, Malikowska-Racia N, Hebda M, Szałaj N, Filipek B, Walczyński K, Malawska B, Bajda M. Jończyk J, et al. Bioorg Chem. 2019 Sep;90:103084. doi: 10.1016/j.bioorg.2019.103084. Epub 2019 Jun 26. Bioorg Chem. 2019. PMID: 31271942