Diagnostic and therapeutic recommendations in pancreatic ductal adenocarcinoma. Recommendations of the Working Group of the Polish Pancreatic Club

Katarzyna Winter; Renata Talar-Wojnarowska; Andrzej Dąbrowski; Małgorzata Degowska; Marek Durlik; Anita Gąsiorowska; Stanisław Głuszek; Grażyna Jurkowska; Aleksandra Kaczka; Paweł Lampe; Tomasz Marek; Anna Nasierowska-Guttmejer; Ewa Nowakowska-Duława; Grażyna Rydzewska; Janusz Strzelczyk; Zbigniew Śledziński; Ewa Małecka-Panas

doi:10.5114/pg.2019.83422

Diagnostic and therapeutic recommendations in pancreatic ductal adenocarcinoma. Recommendations of the Working Group of the Polish Pancreatic Club

Prz Gastroenterol. 2019;14(1):1-18. doi: 10.5114/pg.2019.83422. Epub 2019 Mar 12.

Authors

Katarzyna Winter¹, Renata Talar-Wojnarowska¹, Andrzej Dąbrowski², Małgorzata Degowska³, Marek Durlik⁴, Anita Gąsiorowska⁵, Stanisław Głuszek⁶, Grażyna Jurkowska², Aleksandra Kaczka⁷, Paweł Lampe⁸, Tomasz Marek⁹, Anna Nasierowska-Guttmejer¹⁰, Ewa Nowakowska-Duława⁹, Grażyna Rydzewska³, Janusz Strzelczyk¹¹, Zbigniew Śledziński¹², Ewa Małecka-Panas¹

Affiliations

¹ Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland.
² Department of Gastroenterology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland.
³ Clinical Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland.
⁴ Department of Gastroenterological Surgery and Transplantation Medicine, Central Clinical Hospital of the Ministry of the Internal Affairs and Administration, Warsaw, Poland.
⁵ Department of Gastroenterology, Medical University of Lodz, Lodz, Poland.
⁶ Department of Surgery and Surgical Nursing with the Scientific Research Laboratory, Institute of Medical Sciences, Faculty of Medicine and Health Sciences, Jan Kochanowski University, Kielce, Poland.
⁷ Department of Clinical Nutrition and Gastroenterological Diagnostics, Medical University of Lodz, Lodz, Poland.
⁸ Department of Gastrointestinal Surgery, School of Medicine, Medical University of Silesia, Katowice, Poland.
⁹ Department of Gastroenterology and Hepatology, Medical University of Silesia, Katowice, Poland.
¹⁰ Pathology Department, Jan Kochanowski University, Kielce, Poland.
¹¹ Department of Transplant and General Surgery, Medical University of Lodz, Lodz, Poland.
¹² Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland.

Abstract

These recommendations refer to the current management in pancreatic ductal adenocarcinoma (PDAC), a neoplasia characterised by an aggressive course and extremely poor prognosis. The recommendations regard diagnosis, surgical, adjuvant and palliative treatment, with consideration given to endoscopic and surgical methods. A vast majority of the statements are based on data obtained in clinical studies and experts' recommendations on PDAC management, including the following guidelines: International Association of Pancreatology/European Pancreatic Club (IAP/EPC), American Society of Clinical Oncology (ASCO), European Society for Medical Oncology (ESMO), National Comprehensive Cancer Network (NCCN) and Polish Society of Gastroenterology (PSG) and The National Institute for Health and Care Excellence (NICE). All recommendations were voted on by members of the Working Group of the Polish Pancreatic Club. Results of the voting and brief comments are provided with each recommendation.

Keywords: diagnosis; guidelines; pancreatic ductal adenocarcinoma; recommendations; treatment.