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Page 1
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells.
Belan O, Sebald M, Adamowicz M, Anand R, Vancevska A, Neves J, Grinkevich V, Hewitt G, Segura-Bayona S, Bellelli R, Robinson HMR, Higgins GS, Smith GCM, West SC, Rueda DS, Boulton SJ. Belan O, et al. Among authors: adamowicz m. Mol Cell. 2022 Dec 15;82(24):4664-4680.e9. doi: 10.1016/j.molcel.2022.11.008. Epub 2022 Nov 30. Mol Cell. 2022. PMID: 36455556 Free article.
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW. Demin AA, et al. Among authors: adamowicz m. Mol Cell. 2021 Jul 15;81(14):3018-3030.e5. doi: 10.1016/j.molcel.2021.05.009. Epub 2021 Jun 7. Mol Cell. 2021. PMID: 34102106 Free PMC article.
Breaking up with ATM.
Adamowicz M. Adamowicz M. J Immunol Sci. 2018 Jan;2(1):26-31. Epub 2018 Jan 18. J Immunol Sci. 2018. PMID: 29652413 Free PMC article.
NOTCH1 modulates activity of DNA-PKcs.
Adamowicz M, d'Adda di Fagagna F, Vermezovic J. Adamowicz M, et al. Mutat Res. 2018 Mar;808:20-27. doi: 10.1016/j.mrfmmm.2018.01.003. Mutat Res. 2018. PMID: 29482073
BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment.
D'Alessandro G, Whelan DR, Howard SM, Vitelli V, Renaudin X, Adamowicz M, Iannelli F, Jones-Weinert CW, Lee M, Matti V, Lee WTC, Morten MJ, Venkitaraman AR, Cejka P, Rothenberg E, d'Adda di Fagagna F. D'Alessandro G, et al. Among authors: adamowicz m. Nat Commun. 2018 Dec 18;9(1):5376. doi: 10.1038/s41467-018-07799-2. Nat Commun. 2018. PMID: 30560944 Free PMC article.
Notch is a direct negative regulator of the DNA-damage response.
Vermezovic J, Adamowicz M, Santarpia L, Rustighi A, Forcato M, Lucano C, Massimiliano L, Costanzo V, Bicciato S, Del Sal G, d'Adda di Fagagna F. Vermezovic J, et al. Among authors: adamowicz m. Nat Struct Mol Biol. 2015 May;22(5):417-24. doi: 10.1038/nsmb.3013. Epub 2015 Apr 20. Nat Struct Mol Biol. 2015. PMID: 25895060 Free article.