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Page 1
Identification of small-molecule inhibitors of USP2a.
Eur J Med Chem. 2018 Apr 25;150:261-267. doi: 10.1016/j.ejmech.2018.03.009. Epub 2018 Mar 5.
Eur J Med Chem. 2018.
PMID: 29529503
Development of the Inhibitors that Target the PD-1/PD-L1 Interaction-A Brief Look at Progress on Small Molecules, Peptides and Macrocycles.
Guzik K, Tomala M, Muszak D, Konieczny M, Hec A, Błaszkiewicz U, Pustuła M, Butera R, Dömling A, Holak TA.
Guzik K, et al. Among authors: tomala m.
Molecules. 2019 May 30;24(11):2071. doi: 10.3390/molecules24112071.
Molecules. 2019.
PMID: 31151293
Free PMC article.
Review.
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NMR fragment-based screening for development of the CD44-binding small molecules.
Pustuła M, Czub M, Łabuzek B, Surmiak E, Tomala M, Twarda-Clapa A, Guzik K, Popowicz GM, Holak TA.
Pustuła M, et al. Among authors: tomala m.
Bioorg Chem. 2019 Feb;82:284-289. doi: 10.1016/j.bioorg.2018.10.043. Epub 2018 Oct 25.
Bioorg Chem. 2019.
PMID: 30396062
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A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction.
Surmiak E, Twarda-Clapa A, Zak KM, Musielak B, Tomala MD, Kubica K, Grudnik P, Madej M, Jablonski M, Potempa J, Kalinowska-Tluscik J, Dömling A, Dubin G, Holak TA.
Surmiak E, et al. Among authors: tomala md.
ACS Chem Biol. 2016 Dec 16;11(12):3310-3318. doi: 10.1021/acschembio.6b00596. Epub 2016 Oct 17.
ACS Chem Biol. 2016.
PMID: 27709883
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Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a.
Magiera K, Tomala M, Kubica K, De Cesare V, Trost M, Zieba BJ, Kachamakova-Trojanowska N, Les M, Dubin G, Holak TA, Skalniak L.
Magiera K, et al. Among authors: tomala m.
Cell Chem Biol. 2017 Apr 20;24(4):458-470.e18. doi: 10.1016/j.chembiol.2017.03.002. Epub 2017 Mar 23.
Cell Chem Biol. 2017.
PMID: 28343940
Free PMC article.
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Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.
Skalniak L, Zak KM, Guzik K, Magiera K, Musielak B, Pachota M, Szelazek B, Kocik J, Grudnik P, Tomala M, Krzanik S, Pyrc K, Dömling A, Dubin G, Holak TA.
Skalniak L, et al. Among authors: tomala m.
Oncotarget. 2017 Aug 7;8(42):72167-72181. doi: 10.18632/oncotarget.20050. eCollection 2017 Sep 22.
Oncotarget. 2017.
PMID: 29069777
Free PMC article.
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