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Gain-of-function mutation in complement C2 protein identified in a patient with aHUS.
Urban A, Volokhina E, Felberg A, Stasiłojć G, Blom AM, Jongerius I, van den Heuvel L, Thiel M, Ołdziej S, Arjona E, de Córdoba SR, Okrój M. Urban A, et al. Among authors: thiel m. J Allergy Clin Immunol. 2020 Oct;146(4):916-919.e11. doi: 10.1016/j.jaci.2020.02.014. Epub 2020 Feb 28. J Allergy Clin Immunol. 2020. PMID: 32113979 Free article. No abstract available.
Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein.
Kuźniewska A, Thiel M, Kowalska D, Felberg-Miętka A, Szynkowski P, Ołdziej S, Arjona E, Jongerius I, Rodriguez de Córdoba S, Okrój M, Urban A. Kuźniewska A, et al. Among authors: thiel m. Front Immunol. 2022 Dec 15;13:1061696. doi: 10.3389/fimmu.2022.1061696. eCollection 2022. Front Immunol. 2022. PMID: 36591303 Free PMC article.
Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein.
Urban A, Kowalska D, Stasiłojć G, Kuźniewska A, Skrobińska A, Arjona E, Alonso EC, Fenollosa Segarra MÁ, Jongerius I, Spaapen R, Satchell S, Thiel M, Ołdziej S, Rodriguez de Córdoba S, Okrój M. Urban A, et al. Among authors: thiel m. Front Immunol. 2021 Nov 25;12:724361. doi: 10.3389/fimmu.2021.724361. eCollection 2021. Front Immunol. 2021. PMID: 34899688 Free PMC article.
An iron fist in a velvet glove: The cooperation of a novel pyoverdine from Pseudomonas donghuensis P482 with 7-hydroxytropolone is pivotal for its antibacterial activity.
Jafra S, Jabłońska M, Maciąg T, Matuszewska M, Borowicz M, Prusiński M, Żmudzińska W, Thiel M, Czaplewska P, Krzyżanowska DM, Czajkowski R. Jafra S, et al. Among authors: thiel m. Environ Microbiol. 2024 Jan;26(1):e16559. doi: 10.1111/1462-2920.16559. Epub 2023 Dec 27. Environ Microbiol. 2024. PMID: 38151794