Refractive and topographic effects of single-segment intrastromal corneal ring segments in eyes with moderate to severe keratoconus and inferior cones

J Cataract Refract Surg. 2015 Jul;41(7):1434-40. doi: 10.1016/j.jcrs.2014.10.037. Epub 2015 Jul 29.

Abstract

Purpose: To evaluate the efficacy and safety of a single intrastromal corneal ring segment (ICRS) (450 μm Intacs SK) in moderate to severe keratoconic eyes with an inferiorly located cone and a noninvolved center.

Setting: Ophthalmology Department, American University of Beirut Medical Center, Beirut, Lebanon.

Design: Retrospective case series.

Methods: The uncorrected (UDVA) and corrected (CDVA) distance visual acuities, central and inferior maximum topographic keratometry (K) values, manifest cylinder, and spherical equivalent (SE) were recorded preoperatively and 1 week and 1, 3, and 6 months postoperatively.

Results: Thirty eyes were studied. The mean age was 29.6 years ± 8.0 (SD). The mean preoperative UDVA and CDVA were 20/86 and 20/42, respectively. The mean center K was 49.14 ± 4.39 diopters (D); the mean maximum K, 56.78 ± 6.02 D; and the mean center K - maximum K, -7.45 ± 5.61 D. The mean SE and cylinder were -2.24 ± 2.32 D and -4.33 ± 1.43 D, respectively, with sphere ranging from +2.00 to -18.00 D. At 6 months, the UDVA improved to 20/32. The mean SE was -1.02 ± 2.04 D (P = .0330); the mean cylinder, -1.67 ± 1.00 D (P < .00); and the mean center K - maximum K, -4.92 ± 4.36 D (P < .05). The CDVA improved more than 2 lines; no eye lost any lines. Topographic indices improved in all eyes.

Conclusions: Single ICRS implantation in eyes with moderate to severe keratoconus and inferiorly located cones was safe and effective. The development of a nomogram relying more on topographic data is suggested.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Corneal Stroma / physiopathology
  • Corneal Stroma / surgery*
  • Corneal Topography*
  • Corneal Wavefront Aberration / physiopathology
  • Female
  • Humans
  • Keratoconus / physiopathology
  • Keratoconus / surgery*
  • Male
  • Middle Aged
  • Polymethyl Methacrylate*
  • Prostheses and Implants*
  • Prosthesis Implantation
  • Refraction, Ocular / physiology*
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity / physiology*
  • Young Adult

Substances

  • Polymethyl Methacrylate