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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 6
2003 2
2004 3
2005 1
2006 3
2007 1
2008 4
2009 5
2010 4
2011 5
2012 6
2013 5
2014 9
2015 10
2016 2
2017 4
2018 2
2019 3
2021 3
2022 3
2023 3
2024 0

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78 results

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Page 1
Prospective derivation of a living organoid biobank of colorectal cancer patients.
van de Wetering M, Francies HE, Francis JM, Bounova G, Iorio F, Pronk A, van Houdt W, van Gorp J, Taylor-Weiner A, Kester L, McLaren-Douglas A, Blokker J, Jaksani S, Bartfeld S, Volckman R, van Sluis P, Li VS, Seepo S, Sekhar Pedamallu C, Cibulskis K, Carter SL, McKenna A, Lawrence MS, Lichtenstein L, Stewart C, Koster J, Versteeg R, van Oudenaarden A, Saez-Rodriguez J, Vries RG, Getz G, Wessels L, Stratton MR, McDermott U, Meyerson M, Garnett MJ, Clevers H. van de Wetering M, et al. Cell. 2015 May 7;161(4):933-45. doi: 10.1016/j.cell.2015.03.053. Cell. 2015. PMID: 25957691 Free PMC article.
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.
Herpers B, Eppink B, James MI, Cortina C, Cañellas-Socias A, Boj SF, Hernando-Momblona X, Glodzik D, Roovers RC, van de Wetering M, Bartelink-Clements C, Zondag-van der Zande V, Mateos JG, Yan K, Salinaro L, Basmeleh A, Fatrai S, Maussang D, Lammerts van Bueren JJ, Chicote I, Serna G, Cabellos L, Ramírez L, Nuciforo P, Salazar R, Santos C, Villanueva A, Stephan-Otto Attolini C, Sancho E, Palmer HG, Tabernero J, Stratton MR, de Kruif J, Logtenberg T, Clevers H, Price LS, Vries RGJ, Batlle E, Throsby M. Herpers B, et al. Among authors: van de wetering m. Nat Cancer. 2022 Apr;3(4):418-436. doi: 10.1038/s43018-022-00359-0. Epub 2022 Apr 25. Nat Cancer. 2022. PMID: 35469014 Free article.
Long-term culture of genome-stable bipotent stem cells from adult human liver.
Huch M, Gehart H, van Boxtel R, Hamer K, Blokzijl F, Verstegen MM, Ellis E, van Wenum M, Fuchs SA, de Ligt J, van de Wetering M, Sasaki N, Boers SJ, Kemperman H, de Jonge J, Ijzermans JN, Nieuwenhuis EE, Hoekstra R, Strom S, Vries RR, van der Laan LJ, Cuppen E, Clevers H. Huch M, et al. Among authors: van de wetering m. Cell. 2015 Jan 15;160(1-2):299-312. doi: 10.1016/j.cell.2014.11.050. Epub 2014 Dec 18. Cell. 2015. PMID: 25533785 Free PMC article.
Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation.
Lin L, DeMartino J, Wang D, van Son GJF, van der Linden R, Begthel H, Korving J, Andersson-Rolf A, van den Brink S, Lopez-Iglesias C, van de Wetering WJ, Balwierz A, Margaritis T, van de Wetering M, Peters PJ, Drost J, van Es JH, Clevers H. Lin L, et al. Among authors: van de wetering m. Science. 2023 Oct 27;382(6669):451-458. doi: 10.1126/science.adi2246. Epub 2023 Oct 26. Science. 2023. PMID: 37883554
Xenograft and organoid model systems in cancer research.
Bleijs M, van de Wetering M, Clevers H, Drost J. Bleijs M, et al. Among authors: van de wetering m. EMBO J. 2019 Aug 1;38(15):e101654. doi: 10.15252/embj.2019101654. Epub 2019 Jul 8. EMBO J. 2019. PMID: 31282586 Free PMC article. Review.
Sequential cancer mutations in cultured human intestinal stem cells.
Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H. Drost J, et al. Among authors: van de wetering m. Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29. Nature. 2015. PMID: 25924068
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.
Huch M, Dorrell C, Boj SF, van Es JH, Li VS, van de Wetering M, Sato T, Hamer K, Sasaki N, Finegold MJ, Haft A, Vries RG, Grompe M, Clevers H. Huch M, et al. Among authors: van de wetering m. Nature. 2013 Feb 14;494(7436):247-50. doi: 10.1038/nature11826. Epub 2013 Jan 27. Nature. 2013. PMID: 23354049 Free PMC article.
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.
Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H. Sato T, et al. Among authors: van de wetering m. Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28. Nature. 2011. PMID: 21113151 Free PMC article.
78 results