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Showing results for manual arcila
Your search for Manuel Arcila retrieved no results
Illuminating the druggable genome through patent bioactivity data.
Magariños MP, Gaulton A, Félix E, Kiziloren T, Arcila R, Oprea TI, Leach AR. Magariños MP, et al. PeerJ. 2023 May 2;11:e15153. doi: 10.7717/peerj.15153. eCollection 2023. PeerJ. 2023. PMID: 37151295 Free PMC article.
The overall goal was to select a smaller number of patents that could be manually curated and incorporated into the ChEMBL database. Using relatively simple annotation and filtering pipelines, we have been able to identify a substantial number of patents containing quantit …
The overall goal was to select a smaller number of patents that could be manually curated and incorporated into the ChEMBL database. …
The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods.
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. Zdrazil B, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D1180-D1192. doi: 10.1093/nar/gkad1004. Nucleic Acids Res. 2024. PMID: 37933841 Free PMC article.
ChEMBL (https://www.ebi.ac.uk/chembl/) is a manually curated, high-quality, large-scale, open, FAIR and Global Core Biodata Resource of bioactive molecules with drug-like properties, previously described in the 2012, 2014, 2017 and 2019 Nucleic Acids Research Database Issu …
ChEMBL (https://www.ebi.ac.uk/chembl/) is a manually curated, high-quality, large-scale, open, FAIR and Global Core Biodata Resource …
Rapid EGFR Mutation Detection Using the Idylla Platform: Single-Institution Experience of 1200 Cases Analyzed by an In-House Developed Pipeline and Comparison with Concurrent Next-Generation Sequencing Results.
Momeni-Boroujeni A, Salazar P, Zheng T, Mensah N, Rijo I, Dogan S, Yao J, Moung C, Vanderbilt C, Benhamida J, Chang J, Travis W, Rekhtman N, Ladanyi M, Nafa K, Arcila ME. Momeni-Boroujeni A, et al. J Mol Diagn. 2021 Mar;23(3):310-322. doi: 10.1016/j.jmoldx.2020.11.009. Epub 2020 Dec 18. J Mol Diagn. 2021. PMID: 33346146 Free PMC article.
Validation and experience using an in-house developed analysis pipeline, enhanced with a manual review algorithm is described. Results are compared with corresponding NGS results. ...Discordances involved missed mutations by both assays associated with low tumor/low input. …
Validation and experience using an in-house developed analysis pipeline, enhanced with a manual review algorithm is described. Result …
Novel Modification of HistoGel-Based Cell Block Preparation Method: Improved Sufficiency for Molecular Studies.
Rekhtman N, Buonocore DJ, Rudomina D, Friedlander M, Dsouza C, Aggarwal G, Arcila M, Edelweiss M, Lin O. Rekhtman N, et al. Arch Pathol Lab Med. 2018 Apr;142(4):529-535. doi: 10.5858/arpa.2017-0030-OA. Epub 2017 Nov 2. Arch Pathol Lab Med. 2018. PMID: 29095036 Free PMC article.
Sufficiency of cell block material for potential molecular studies was estimated by manual cell quantitation. RESULTS: - The key modification in the new method was pretreatment of the pelleted cells with 95% ethanol before the addition of HistoGel (HistoGel + ethanol metho …
Sufficiency of cell block material for potential molecular studies was estimated by manual cell quantitation. RESULTS: - The key modi …
Ultrarapid EGFR Mutation Screening Followed by Comprehensive Next-Generation Sequencing: A Feasible, Informative Approach for Lung Carcinoma Cytology Specimens With a High Success Rate.
Arcila ME, Yang SR, Momeni A, Mata DA, Salazar P, Chan R, Elezovic D, Benayed R, Zehir A, Buonocore DJ, Rekhtman N, Lin O, Ladanyi M, Nafa K. Arcila ME, et al. JTO Clin Res Rep. 2020 Sep;1(3):100077. doi: 10.1016/j.jtocrr.2020.100077. Epub 2020 Jul 18. JTO Clin Res Rep. 2020. PMID: 33511359 Free PMC article.
The Idylla automated results were concordant with those obtained by NGS in 96.2% (153 of 159) of cases and improved to 98.7% (157 of 159) after incorporation of manual review criteria to supplement automated calling, resulting in a diagnostic sensitivity of 95.6% (95% conf …
The Idylla automated results were concordant with those obtained by NGS in 96.2% (153 of 159) of cases and improved to 98.7% (157 of 159) af …
Next-Generation Assessment of Human Epidermal Growth Factor Receptor 2 (ERBB2) Amplification Status: Clinical Validation in the Context of a Hybrid Capture-Based, Comprehensive Solid Tumor Genomic Profiling Assay.
Ross DS, Zehir A, Cheng DT, Benayed R, Nafa K, Hechtman JF, Janjigian YY, Weigelt B, Razavi P, Hyman DM, Baselga J, Berger MF, Ladanyi M, Arcila ME. Ross DS, et al. J Mol Diagn. 2017 Mar;19(2):244-254. doi: 10.1016/j.jmoldx.2016.09.010. Epub 2016 Dec 25. J Mol Diagn. 2017. PMID: 28027945 Free PMC article.
The Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT) assay, a hybrid capture-based NGS assay interrogating the coding regions of 410 cancer-related genes, was performed on manually macrodissected unstained sections from forma …
The Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT) assay, a hybrid capture-based NGS assay …