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Direct Inhibition of SARS-CoV-2 Spike Protein by Peracetic Acid.
Yamamoto Y, Nakano Y, Murae M, Shimizu Y, Sakai S, Ogawa M, Mizukami T, Inoue T, Onodera T, Takahashi Y, Wakita T, Fukasawa M, Miyazaki S, Noguchi K. Yamamoto Y, et al. Among authors: murae m. Int J Mol Sci. 2022 Dec 20;24(1):20. doi: 10.3390/ijms24010020. Int J Mol Sci. 2022. PMID: 36613459 Free PMC article.
The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione.
Murae M, Shimizu Y, Yamamoto Y, Kobayashi A, Houri M, Inoue T, Irie T, Gemba R, Kondo Y, Nakano Y, Miyazaki S, Yamada D, Saitoh A, Ishii I, Onodera T, Takahashi Y, Wakita T, Fukasawa M, Noguchi K. Murae M, et al. Biochem Biophys Res Commun. 2022 Mar 15;597:30-36. doi: 10.1016/j.bbrc.2022.01.106. Epub 2022 Jan 29. Biochem Biophys Res Commun. 2022. PMID: 35123263 Free PMC article.
The combination of levodopa with levodopa-metabolizing enzyme inhibitors prevents severe fever with thrombocytopenia syndrome virus infection in vitro more effectively than single levodopa.
Ogawa M, Murae M, Mizukami T, Gemba R, Irie T, Shimojima M, Ebihara H, Noguchi K, Fukasawa M. Ogawa M, et al. Among authors: murae m. J Infect Chemother. 2023 May;29(5):549-553. doi: 10.1016/j.jiac.2023.02.017. Epub 2023 Mar 3. J Infect Chemother. 2023. PMID: 36871824