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Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration.
Nozaki Y, Hikita H, Tanaka S, Fukumoto K, Urabe M, Sato K, Myojin Y, Doi A, Murai K, Sakane S, Saito Y, Kodama T, Sakamori R, Tatsumi T, Takehara T. Nozaki Y, et al. Among authors: urabe m. Sci Rep. 2021 Feb 9;11(1):3363. doi: 10.1038/s41598-021-83082-7. Sci Rep. 2021. PMID: 33564095 Free PMC article.
5-Fluorouracil/L-Leucovorin Plus Oxaliplatin (FOLFOX) Regimen as Salvage Chemotherapy for Patients with Unresectable Pancreatic Cancer Receiving Gemcitabine and Nab-Paclitaxel and 5-Fluorouracil/L-Leucovorin Plus Nanoliposomal Irinotecan: Preliminary Results from Clinical Practice.
Yamai T, Ikezawa K, Kawamoto Y, Hirao T, Higashi S, Daiku K, Maeda S, Abe Y, Urabe M, Kai Y, Takada R, Nakabori T, Uehara H, Ohkawa K. Yamai T, et al. Among authors: urabe m. Curr Oncol. 2022 Apr 11;29(4):2644-2649. doi: 10.3390/curroncol29040216. Curr Oncol. 2022. PMID: 35448190 Free PMC article.
Early detection of venous thromboembolism after the initiation of chemotherapy predicts a poor prognosis in patients with unresectable metastatic pancreatic cancer who underwent first-line chemotherapy with gemcitabine plus nab-paclitaxel.
Yamai T, Ikezawa K, Hiraga E, Kawamoto Y, Hirao T, Higashi S, Daiku K, Maeda S, Abe Y, Urabe M, Kai Y, Takada R, Nakabori T, Fukutake N, Uehara H, Fujita M, Ohkawa K. Yamai T, et al. Among authors: urabe m. PLoS One. 2022 Mar 1;17(3):e0264653. doi: 10.1371/journal.pone.0264653. eCollection 2022. PLoS One. 2022. PMID: 35231078 Free PMC article.
Gab1 in livers with persistent hepatocyte apoptosis has an antiapoptotic effect and reduces chronic liver injury, fibrosis, and tumorigenesis.
Mizutani N, Hikita H, Saito Y, Myojin Y, Sato K, Urabe M, Kurahashi T, Shiode Y, Sakane S, Murai K, Nozaki Y, Kodama T, Sakamori R, Yoshida Y, Tatsumi T, Takehara T. Mizutani N, et al. Among authors: urabe m. Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1;320(6):G958-G968. doi: 10.1152/ajpgi.00370.2020. Epub 2021 Mar 31. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33787344 Free article.
21 results