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Discovery of (E)-4-styrylphenoxy-propanamide: A dual PPARα/γ partial agonist that regulates high-density lipoprotein-cholesterol levels, modulates adipogenesis, and improves glucose tolerance in diet-induced obese mice.
Dutra LA, Lacerda MG, Destro Inácio M, Martins JWL, Lopes Silva AC, Bento da Silva P, Chorilli M, Amato AA, Baviera AM, Passarelli M, Guido RVC, Dos Santos JL. Dutra LA, et al. Among authors: destro inacio m. Bioorg Chem. 2022 Mar;120:105600. doi: 10.1016/j.bioorg.2022.105600. Epub 2022 Jan 10. Bioorg Chem. 2022. PMID: 35078048
Trigonelline and curcumin alone, but not in combination, counteract oxidative stress and inflammation and increase glycation product detoxification in the liver and kidney of mice with high-fat diet-induced obesity.
Costa MC, Lima TFO, Arcaro CA, Inacio MD, Batista-Duharte A, Carlos IZ, Spolidorio LC, Assis RP, Brunetti IL, Baviera AM. Costa MC, et al. Among authors: inacio md. J Nutr Biochem. 2020 Feb;76:108303. doi: 10.1016/j.jnutbio.2019.108303. Epub 2019 Nov 23. J Nutr Biochem. 2020. PMID: 31812909
Curcumin, Alone or in Combination with Aminoguanidine, Increases Antioxidant Defenses and Glycation Product Detoxification in Streptozotocin-Diabetic Rats: A Therapeutic Strategy to Mitigate Glycoxidative Stress.
Lima TFO, Costa MC, Figueiredo ID, Inácio MD, Rodrigues MR, Assis RP, Baviera AM, Brunetti IL. Lima TFO, et al. Among authors: inacio md. Oxid Med Cell Longev. 2020 May 20;2020:1036360. doi: 10.1155/2020/1036360. eCollection 2020. Oxid Med Cell Longev. 2020. PMID: 32566072 Free PMC article.
Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats.
Inácio MD, Rafacho A, de Paula Camaforte NA, Teixeira P, Vareda PMP, Violato NM, Bosqueiro JR. Inácio MD, et al. Int J Endocrinol. 2018 Nov 8;2018:3257812. doi: 10.1155/2018/3257812. eCollection 2018. Int J Endocrinol. 2018. PMID: 30532777 Free PMC article.