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Page 1
Potential epigenetic therapeutics for atherosclerosis treatment.
Nicorescu I, Dallinga GM, de Winther MPJ, Stroes ESG, Bahjat M. Nicorescu I, et al. Among authors: bahjat m. Atherosclerosis. 2019 Feb;281:189-197. doi: 10.1016/j.atherosclerosis.2018.10.006. Epub 2018 Oct 8. Atherosclerosis. 2019. PMID: 30340764 Review.
BET protein inhibitor apabetalone (RVX-208) suppresses pro-inflammatory hyper-activation of monocytes from patients with cardiovascular disease and type 2 diabetes.
Wasiak S, Dzobo KE, Rakai BD, Kaiser Y, Versloot M, Bahjat M, Stotz SC, Fu L, Sweeney M, Johansson JO, Wong NCW, Stroes ESG, Kroon J, Kulikowski E. Wasiak S, et al. Among authors: bahjat m. Clin Epigenetics. 2020 Nov 11;12(1):166. doi: 10.1186/s13148-020-00943-0. Clin Epigenetics. 2020. PMID: 33172487 Free PMC article.
Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a).
Stiekema LCA, Prange KHM, Hoogeveen RM, Verweij SL, Kroon J, Schnitzler JG, Dzobo KE, Cupido AJ, Tsimikas S, Stroes ESG, de Winther MPJ, Bahjat M. Stiekema LCA, et al. Among authors: bahjat m. Eur Heart J. 2020 Jun 21;41(24):2262-2271. doi: 10.1093/eurheartj/ehaa171. Eur Heart J. 2020. PMID: 32268367 Free PMC article.
The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling.
Ochodnicka-Mackovicova K, Bahjat M, Maas C, van der Veen A, Bloedjes TA, de Bruin AM, van Andel H, Schrader CE, Hendriks RW, Verhoeyen E, Bende RJ, van Noesel CJ, Guikema JE. Ochodnicka-Mackovicova K, et al. Among authors: bahjat m. J Immunol. 2016 Oct 1;197(7):2918-29. doi: 10.4049/jimmunol.1501989. Epub 2016 Aug 24. J Immunol. 2016. PMID: 27559048