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Activation of CD8+ T Cells in Chronic Obstructive Pulmonary Disease Lung.
Am J Respir Crit Care Med. 2023 Dec 1;208(11):1177-1195. doi: 10.1164/rccm.202305-0924OC.
Am J Respir Crit Care Med. 2023.
PMID: 37756440
A lower X-gate in TASK channels traps inhibitors within the vestibule.
Rödström KEJ, Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, Burgess-Brown NA, Tucker SJ, Müller T, Decher N, Carpenter EP.
Rödström KEJ, et al. Among authors: platzk m.
Nature. 2020 Jun;582(7812):443-447. doi: 10.1038/s41586-020-2250-8. Epub 2020 Apr 29.
Nature. 2020.
PMID: 32499642
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5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis.
Ramírez D, Mejia-Gutierrez M, Insuasty B, Rinné S, Kiper AK, Platzk M, Müller T, Decher N, Quiroga J, De-la-Torre P, González W.
Ramírez D, et al. Among authors: platzk m.
Molecules. 2021 Jun 25;26(13):3897. doi: 10.3390/molecules26133897.
Molecules. 2021.
PMID: 34202296
Free PMC article.
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