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2015 2
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Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease.
Zaręba P, Łątka K, Mazur G, Gryzło B, Pasieka A, Godyń J, Panek D, Skrzypczak-Wiercioch A, Höfner GC, Latacz G, Maj M, Espargaró A, Sabaté R, Jóźwiak K, Wanner KT, Sałat K, Malawska B, Kulig K, Bajda M. Zaręba P, et al. Among authors: maj m. Eur J Med Chem. 2023 Dec 5;261:115832. doi: 10.1016/j.ejmech.2023.115832. Epub 2023 Oct 7. Eur J Med Chem. 2023. PMID: 37837674 Free article.
Application of the SMALP technology to the isolation of GPCRs from low-yielding cell lines.
Tedesco D, Maj M, Malarczyk P, Cingolani A, Zaffagnini M, Wnorowski A, Czapiński J, Benelli T, Mazzoni R, Bartolini M, Jóźwiak K. Tedesco D, et al. Among authors: maj m. Biochim Biophys Acta Biomembr. 2021 Sep 1;1863(9):183641. doi: 10.1016/j.bbamem.2021.183641. Epub 2021 May 10. Biochim Biophys Acta Biomembr. 2021. PMID: 33984320 Free article.
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation.
Malek R, Simakov A, Davis A, Maj M, Bernard PJ, Wnorowski A, Martin H, Marco-Contelles J, Chabchoub F, Dallemagne P, Rochais C, Jozwiak K, Ismaili L. Malek R, et al. Among authors: maj m. Molecules. 2022 Dec 22;28(1):71. doi: 10.3390/molecules28010071. Molecules. 2022. PMID: 36615267 Free PMC article.
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease.
Chioua M, Buzzi E, Moraleda I, Iriepa I, Maj M, Wnorowski A, Giovannini C, Tramarin A, Portali F, Ismaili L, López-Alvarado P, Bolognesi ML, Jóźwiak K, Menéndez JC, Marco-Contelles J, Bartolini M. Chioua M, et al. Among authors: maj m. Eur J Med Chem. 2018 Jul 15;155:839-846. doi: 10.1016/j.ejmech.2018.06.044. Epub 2018 Jun 19. Eur J Med Chem. 2018. PMID: 29958119
25 results