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Page 1
Design of functional intrinsically disordered proteins.
Protein Eng Des Sel. 2024 Jan 29;37:gzae004. doi: 10.1093/protein/gzae004.
Protein Eng Des Sel. 2024.
PMID: 38431892
The engineered peptide construct NCAM1-Aβ inhibits fibrillization of the human prion protein (PrP).
Gielnik M, Zhukova L, Zhukov I, Gräslund A, Kozak M, Wärmländer S.
Gielnik M, et al.
Acta Biochim Pol. 2022 Feb 10;69(1):257-261. doi: 10.18388/abp.2020_5679.
Acta Biochim Pol. 2022.
PMID: 35143147
Free article.
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Effect of Posttranslational Modifications on the Structure and Activity of FTO Demethylase.
Marcinkowski M, Pilžys T, Garbicz D, Piwowarski J, Mielecki D, Nowaczyk G, Taube M, Gielnik M, Kozak M, Winiewska-Szajewska M, Szołajska E, Dębski J, Maciejewska AM, Przygońska K, Ferenc K, Grzesiuk E, Poznański J.
Marcinkowski M, et al. Among authors: gielnik m.
Int J Mol Sci. 2021 Apr 26;22(9):4512. doi: 10.3390/ijms22094512.
Int J Mol Sci. 2021.
PMID: 33925955
Free PMC article.
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Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu(II) and Zn(II) Ions.
Gielnik M, Szymańska A, Dong X, Jarvet J, Svedružić ŽM, Gräslund A, Kozak M, Wärmländer SKTS.
Gielnik M, et al.
Biochemistry. 2023 Jun 6;62(11):1689-1705. doi: 10.1021/acs.biochem.3c00129. Epub 2023 May 10.
Biochemistry. 2023.
PMID: 37163663
Free PMC article.
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Characterization of Uranyl (UO22+) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation.
Berntsson E, Vosough F, Noormägi A, Padari K, Asplund F, Gielnik M, Paul S, Jarvet J, Tõugu V, Roos PM, Kozak M, Gräslund A, Barth A, Pooga M, Palumaa P, Wärmländer SKTS.
Berntsson E, et al. Among authors: gielnik m.
ACS Chem Neurosci. 2023 Aug 2;14(15):2618-2633. doi: 10.1021/acschemneuro.3c00130. Epub 2023 Jul 24.
ACS Chem Neurosci. 2023.
PMID: 37487115
Free PMC article.
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Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein.
Gielnik M, Taube M, Zhukova L, Zhukov I, Wärmländer SKTS, Svedružić Ž, Kwiatek WM, Gräslund A, Kozak M.
Gielnik M, et al.
Sci Rep. 2021 Nov 4;11(1):21703. doi: 10.1038/s41598-021-00495-0.
Sci Rep. 2021.
PMID: 34737343
Free PMC article.
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PrP (58-93) peptide from unstructured N-terminal domain of human prion protein forms amyloid-like fibrillar structures in the presence of Zn2+ ions.
Gielnik M, Pietralik Z, Zhukov I, Szymańska A, Kwiatek WM, Kozak M.
Gielnik M, et al.
RSC Adv. 2019 Jul 17;9(39):22211-22219. doi: 10.1039/c9ra01510h. eCollection 2019 Jul 17.
RSC Adv. 2019.
PMID: 35519468
Free PMC article.
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