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Uterine sarcomas: clinical practice guidelines for diagnosis, treatment, and follow-up, by Spanish group for research on sarcomas (GEIS).
Pérez-Fidalgo JA, Ortega E, Ponce J, Redondo A, Sevilla I, Valverde C, Isern Verdum J, de Alava E, Galera López M, Marquina G, Sebio A. Pérez-Fidalgo JA, et al. Ther Adv Med Oncol. 2023 Mar 28;15:17588359231157645. doi: 10.1177/17588359231157645. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 37007636 Free PMC article. Review.
Mechanistic insights into glycoside 3-oxidases involved in C-glycoside metabolism in soil microorganisms.
Taborda A, Frazão T, Rodrigues MV, Fernández-Luengo X, Sancho F, Lucas MF, Frazão C, Melo EP, Ventura MR, Masgrau L, Borges PT, Martins LO. Taborda A, et al. Nat Commun. 2023 Nov 14;14(1):7289. doi: 10.1038/s41467-023-42000-3. Nat Commun. 2023. PMID: 37963862 Free PMC article.
Here, we report that PsG3Ox oxidizes at 50,000-fold higher specificity (k(cat)/K(m)) the glucose moiety of mangiferin to 3-keto-mangiferin than free D-glucose to 2-keto-glucose. ...
Here, we report that PsG3Ox oxidizes at 50,000-fold higher specificity (k(cat)/K(m)) the glucose moiety of mangiferin to 3-keto-mangi …
Flexible active-site loops fine-tune substrate specificity of hyperthermophilic metallo-oxidases.
Brissos V, Borges PT, Sancho F, Lucas MF, Frazão C, Conzuelo F, Martins LO. Brissos V, et al. J Biol Inorg Chem. 2024 Jan 16. doi: 10.1007/s00775-023-02040-y. Online ahead of print. J Biol Inorg Chem. 2024. PMID: 38227199
Six rounds of error-prone PCR and DNA shuffling followed by high-throughput screening lead to the identification of a hit variant with a 220-fold increased efficiency (k(cat)/K(m)) than the wild-type for 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) withou …
Six rounds of error-prone PCR and DNA shuffling followed by high-throughput screening lead to the identification of a hit variant with a 220 …
Measuring the cost of a pediatric vaccine administration in the UK.
Mokiou S, Standaert B, Li X, De Cock E. Mokiou S, et al. Vaccine. 2018 Jan 4;36(2):237-242. doi: 10.1016/j.vaccine.2017.11.042. Epub 2017 Dec 6. Vaccine. 2018. PMID: 29208324 Free article.
A prospective, non-interventional study using Time & Motion (T&M) methodology was used to measure time for activities happening on the day of vaccination. ...Third, the time for each task and for all tasks combined during the T&M study was analyzed using …
A prospective, non-interventional study using Time & Motion (T&M) methodology was used to measure time for activities happeni …