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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1977 1
1980 3
1981 1
1982 2
1983 1
1984 1
1985 2
1986 2
1987 1
1988 2
1989 4
1990 2
1991 3
1992 6
1993 3
1994 1
1995 3
1996 5
1997 6
1998 3
1999 11
2000 7
2001 14
2002 16
2003 25
2004 18
2005 11
2006 12
2007 18
2008 16
2009 13
2010 13
2011 21
2012 26
2013 28
2014 20
2015 22
2016 20
2017 22
2018 17
2019 17
2020 27
2021 19
2022 18
2023 20
2024 16

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475 results

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Page 1
Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.
Vergote I, Gonzalez-Martin A, Lorusso D, Gourley C, Mirza MR, Kurtz JE, Okamoto A, Moore K, Kridelka F, McNeish I, Reuss A, Votan B, du Bois A, Mahner S, Ray-Coquard I, Kohn EC, Berek JS, Tan DSP, Colombo N, Zang R, Concin N, O'Donnell D, Rauh-Hain A, Herrington CS, Marth C, Poveda A, Fujiwara K, Stuart GCE, Oza AM, Bookman MA; participants of the 6th Gynecologic Cancer InterGroup (GCIG) Ovarian Cancer Consensus Conference on Clinical Research. Vergote I, et al. Lancet Oncol. 2022 Aug;23(8):e374-e384. doi: 10.1016/S1470-2045(22)00139-5. Lancet Oncol. 2022. PMID: 35901833 Free PMC article. Review.
Edoxaban versus warfarin in patients with atrial fibrillation.
Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, Waldo AL, Ezekowitz MD, Weitz JI, Špinar J, Ruzyllo W, Ruda M, Koretsune Y, Betcher J, Shi M, Grip LT, Patel SP, Patel I, Hanyok JJ, Mercuri M, Antman EM; ENGAGE AF-TIMI 48 Investigators. Giugliano RP, et al. N Engl J Med. 2013 Nov 28;369(22):2093-104. doi: 10.1056/NEJMoa1310907. Epub 2013 Nov 19. N Engl J Med. 2013. PMID: 24251359 Free article. Clinical Trial.
Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source.
Hart RG, Sharma M, Mundl H, Kasner SE, Bangdiwala SI, Berkowitz SD, Swaminathan B, Lavados P, Wang Y, Wang Y, Davalos A, Shamalov N, Mikulik R, Cunha L, Lindgren A, Arauz A, Lang W, Czlonkowska A, Eckstein J, Gagliardi RJ, Amarenco P, Ameriso SF, Tatlisumak T, Veltkamp R, Hankey GJ, Toni D, Bereczki D, Uchiyama S, Ntaios G, Yoon BW, Brouns R, Endres M, Muir KW, Bornstein N, Ozturk S, O'Donnell MJ, De Vries Basson MM, Pare G, Pater C, Kirsch B, Sheridan P, Peters G, Weitz JI, Peacock WF, Shoamanesh A, Benavente OR, Joyner C, Themeles E, Connolly SJ; NAVIGATE ESUS Investigators. Hart RG, et al. N Engl J Med. 2018 Jun 7;378(23):2191-2201. doi: 10.1056/NEJMoa1802686. Epub 2018 May 16. N Engl J Med. 2018. PMID: 29766772 Free article. Clinical Trial.
Baseline ctDNA gene alterations as a biomarker of survival after panitumumab and chemotherapy in metastatic colorectal cancer.
Shitara K, Muro K, Watanabe J, Yamazaki K, Ohori H, Shiozawa M, Takashima A, Yokota M, Makiyama A, Akazawa N, Ojima H, Yuasa Y, Miwa K, Yasui H, Oki E, Sato T, Naitoh T, Komatsu Y, Kato T, Mori I, Yamanaka K, Hihara M, Soeda J, Misumi T, Yamamoto K, Yamashita R, Akagi K, Ochiai A, Uetake H, Tsuchihara K, Yoshino T. Shitara K, et al. Nat Med. 2024 Mar;30(3):730-739. doi: 10.1038/s41591-023-02791-w. Epub 2024 Feb 12. Nat Med. 2024. PMID: 38347302 Free PMC article.
S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1.
Shima H, Matsumoto M, Ishigami Y, Ebina M, Muto A, Sato Y, Kumagai S, Ochiai K, Suzuki T, Igarashi K. Shima H, et al. Cell Rep. 2017 Dec 19;21(12):3354-3363. doi: 10.1016/j.celrep.2017.11.092. Cell Rep. 2017. PMID: 29262316 Free article.
Knockdown of METTL16 and the m(6)A reader YTHDC1 abolished SAM-responsive regulation of MAT2A. Mutations of the target adenine sites of METTL16 within the 3' UTR revealed that these m(6)As were redundantly required for regulation. MAT2A mRNA methylation by METTL16 i …
Knockdown of METTL16 and the m(6)A reader YTHDC1 abolished SAM-responsive regulation of MAT2A. Mutations of the target adenine sites …
Quantitative Modeling and Simulation in PMDA: A Japanese Regulatory Perspective.
Sato M, Ochiai Y, Kijima S, Nagai N, Ando Y, Shikano M, Nomura Y. Sato M, et al. CPT Pharmacometrics Syst Pharmacol. 2017 Jul;6(7):413-415. doi: 10.1002/psp4.12203. Epub 2017 Jun 1. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28568566 Free PMC article.
In this article, we summarize the number of submissions of quantitative modeling and simulation (M&S) documents in NDAs in Japan, and we describe our current thinking and activities about quantitative M&S in PMDA....
In this article, we summarize the number of submissions of quantitative modeling and simulation (M&S) documents in NDAs in Japan, …
Fibroblast inhibition by tocilizumab enabled gemcitabine/nab-paclitaxel rechallenge for pancreatic cancer.
Mitsunaga S, Ikeda M, Imaoka H, Sasaki M, Watanabe K, Sato A, Aoki K, Ochiai A, Makikawa M, Nishidate M, Yamaguchi K, Terao K, Sawada N, Fujitomo T, Fujii E, Kato A, Tsunoda H. Mitsunaga S, et al. Cancer Sci. 2023 Oct;114(10):4006-4019. doi: 10.1111/cas.15929. Epub 2023 Aug 21. Cancer Sci. 2023. PMID: 37605479 Free PMC article.
Patients initially received TCZ 8 mg/kg on Day 1 and nab-PTX 100 mg/m(2) + GEM 750 mg/m(2) on Days 2, 9, and 16. Before and at the end of Cycle 1, biopsy of liver metastases was performed 3-5 h after levofloxacin (LVFX) administration to measure LVFX infiltration in …
Patients initially received TCZ 8 mg/kg on Day 1 and nab-PTX 100 mg/m(2) + GEM 750 mg/m(2) on Days 2, 9, and 16. Before and at …
Intracellular dynamics of steroid hormone receptor.
Kawata M, Matsuda K, Nishi M, Ogawa H, Ochiai I. Kawata M, et al. Neurosci Res. 2001 Jul;40(3):197-203. doi: 10.1016/s0168-0102(01)00253-x. Neurosci Res. 2001. PMID: 11448510 Review.
Sarcoma-like appearance but pathologic Hodgkin lymphoma.
Harada S, Ando J, Ando M, Azusawa Y, Ochiai T, Hashimoto Y, Hirasawa Y, Komatsu N. Harada S, et al. Int J Hematol. 2021 Jul;114(1):1-2. doi: 10.1007/s12185-021-03169-9. Epub 2021 May 31. Int J Hematol. 2021. PMID: 34059996 No abstract available.
Barriers to typhoid fever vaccine access in endemic countries.
Khan MI, Franco-Paredes C, Sahastrabuddhe S, Ochiai RL, Mogasale V, Gessner BD. Khan MI, et al. Res Rep Trop Med. 2017 Mar 10;8:37-44. doi: 10.2147/RRTM.S97309. eCollection 2017. Res Rep Trop Med. 2017. PMID: 30050343 Free PMC article. Review.
475 results