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Effects of Repetitive Transendocardial CD34+ Cell Transplantation in Patients With Nonischemic Dilated Cardiomyopathy.
Vrtovec B, Poglajen G, Sever M, Zemljic G, Frljak S, Cerar A, Cukjati M, Jaklic M, Cernelc P, Haddad F, Wu JC. Vrtovec B, et al. Circ Res. 2018 Jul 20;123(3):389-396. doi: 10.1161/CIRCRESAHA.117.312170. Epub 2018 Jun 7. Circ Res. 2018. PMID: 29880546 Clinical Trial.
From baseline to 6 months, both groups improved in LVEF (+6.93.3% in group A, P=0.001 and +7.13.5% in group B, P=0.001), NT-proBNP (-578211 pg/mL, P=0.02 and -633305 pg/mL, P=0.01), and 6-minute walk test (+8721 m, P=0.03 and +9225 m, P=0.02). In contrast, we observ …
From baseline to 6 months, both groups improved in LVEF (+6.93.3% in group A, P=0.001 and +7.13.5% in group B, P=0.001), NT-proBNP (-578211 …
Transendocardial CD34+ Cell Therapy does not Increase the Risk of Ventricular Arrhythmias in Patients with Chronic Heart Failure.
Poglajen G, Zemljič G, Cerar A, Frljak S, Jaklič M, Androcec V, Vrtovec B. Poglajen G, et al. Cell Transplant. 2019 Jul;28(7):856-863. doi: 10.1177/0963689719840351. Epub 2019 May 2. Cell Transplant. 2019. PMID: 31046425 Free PMC article.
The average serum creatinine was 9126 mol/L, serum bilirubin 189 mol/L, NT-proBNP 1767 (468, 2446) pg/mL, LVEF 279% and 6' walk test 442123 m. The average scar burden in patients with nonischemic and ischemic DCM was 5815% and 5125% (P=0.48). ...
The average serum creatinine was 9126 mol/L, serum bilirubin 189 mol/L, NT-proBNP 1767 (468, 2446) pg/mL, LVEF 279% and 6' walk test 442123 …