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1994 1
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Page 1
Assessment of Mini-Tablets Coating Uniformity as a Function of Fluid Bed Coater Inlet Conditions.
Turk M, Šibanc R, Dreu R, Frankiewicz M, Sznitowska M. Turk M, et al. Pharmaceutics. 2021 May 18;13(5):746. doi: 10.3390/pharmaceutics13050746. Pharmaceutics. 2021. PMID: 34070006 Free PMC article.
Mini-tablets with a diameter of 2.0, 2.5, and 3.0 mm were coated with hypromellose using two different inlet air distributors as well as inlet airflow rates (130 and 156 m(3)/h). Tartrazine was used as a colorant in the coating layer and the coating uniformity was assessed …
Mini-tablets with a diameter of 2.0, 2.5, and 3.0 mm were coated with hypromellose using two different inlet air distributors as well as inl …
Technology of Orodispersible Polymer Films with Micronized Loratadine-Influence of Different Drug Loadings on Film Properties.
Centkowska K, Ławrecka E, Sznitowska M. Centkowska K, et al. Pharmaceutics. 2020 Mar 10;12(3):250. doi: 10.3390/pharmaceutics12030250. Pharmaceutics. 2020. PMID: 32164345 Free PMC article.
Drug concentrations higher than 30% reduced the film flexibility and tear resistance, depending on the polymer type. LO films with a thickness of 100 m disintegrated within 60-100 s, with no significant influence of the LO content in the range 10%-30%. ...
Drug concentrations higher than 30% reduced the film flexibility and tear resistance, depending on the polymer type. LO films with a thickne …
Studies on the effect of pH on the lipoidal route of penetration across stratum corneum.
Sznitowska M, Janicki S, Baczek A. Sznitowska M, et al. J Control Release. 2001 Oct 19;76(3):327-35. doi: 10.1016/s0168-3659(01)00443-6. J Control Release. 2001. PMID: 11578746
Suspensions of the model compounds in appropriate buffers (0.1-0.2 M) were applied to the intact skin, delipidized skin, skin pretreated with Azone or sodium lauryl sulfate solution and the percutaneous penetration was observed for 28 h. ...
Suspensions of the model compounds in appropriate buffers (0.1-0.2 M) were applied to the intact skin, delipidized skin, skin pretrea …
Comparison of Different Liquid and Semisolid Vehicles Selected for Oral Administration of Pellets and Minitablets with Diazepam: In Vitro Investigation.
Kotlowska H, Szymanska M, Sznitowska M. Kotlowska H, et al. AAPS PharmSciTech. 2020 Jul 31;21(6):213. doi: 10.1208/s12249-020-01761-6. AAPS PharmSciTech. 2020. PMID: 32737624 Free PMC article.
The pellets disintegrated in liquid carriers within 3 min. The drug dissolution rate in 0.1 M HCl depended on the gel viscosity in this medium. The preserved high viscosity of a carmellose gel inhibited the dissolution of diazepam. ...
The pellets disintegrated in liquid carriers within 3 min. The drug dissolution rate in 0.1 M HCl depended on the gel viscosity in th …
Double layer adhesive silicone dressing as a potential dermal drug delivery film in scar treatment.
Mojsiewicz-Pieńkowska K, Jamrógiewicz M, Żebrowska M, Mikolaszek B, Sznitowska M. Mojsiewicz-Pieńkowska K, et al. Int J Pharm. 2015 Mar 15;481(1-2):18-26. doi: 10.1016/j.ijpharm.2015.01.050. Epub 2015 Jan 29. Int J Pharm. 2015. PMID: 25639195 Clinical Trial.
The novel adhesive silicone film was found to possess optimal properties in comparison to commercially available silicone dressing: adhesion in vivo, adhesion in vitro - 11.79N, occlusion F=85% and water vapor permeability in vitro - WVP=105g/m(2)/24h, hydration of stratum …
The novel adhesive silicone film was found to possess optimal properties in comparison to commercially available silicone dressing: adhesion …
Choice of excipients for gelly-like pulp prepared ex tempore "on a spoon"- "placebo" and with sartans.
Wolska E, Kluk A, Zarazińska M, Boniecka M, Sznitowska M. Wolska E, et al. Drug Dev Ind Pharm. 2016;42(6):998-1007. doi: 10.3109/03639045.2015.1103747. Epub 2015 Nov 7. Drug Dev Ind Pharm. 2016. PMID: 26548554
RESULTS: Mixtures of guar gum, lactose and one of the disintegrants (F-Melt M, Prosolv 50, Prosolv Easy, Lycatab, Pharmaburst, Pearlitol) demonstrated the best properties. ...
RESULTS: Mixtures of guar gum, lactose and one of the disintegrants (F-Melt M, Prosolv 50, Prosolv Easy, Lycatab, Pharmaburst, Pearli …
Increased proliferation of skin cells by sublethal doses of sodium lauryl sulfate.
Bloom E, Sznitowska M, Polansky J, Ma ZD, Maibach HI. Bloom E, et al. Dermatology. 1994;188(4):263-8. doi: 10.1159/000247163. Dermatology. 1994. PMID: 8193397
Confluent fibroblasts were stimulated 40%. All stimulations were maximal between 10(-8) and 10(-5) M added SLS. Media conditioned by keratinocytes exposed to 10(-8) M SLS were able to increase the growth of naive keratinocytes by 117%. In all experiments doses of SL …
Confluent fibroblasts were stimulated 40%. All stimulations were maximal between 10(-8) and 10(-5) M added SLS. Media conditioned by …
Physicochemical screening of antimicrobial agents as potential preservatives for submicron emulsions.
Sznitowska M, Janicki S, Dabrowska EA, Gajewska M. Sznitowska M, et al. Eur J Pharm Sci. 2002 Jun;15(5):489-95. doi: 10.1016/s0928-0987(02)00034-9. Eur J Pharm Sci. 2002. PMID: 12036725
Parabens showed the best compatibility but satisfying stability was also observed in emulsions containing phenylethanol, m-cresol and benzalkonium chloride. Partitioning studies revealed poor correlation between aqueous solubility and content of the preservatives in the aq …
Parabens showed the best compatibility but satisfying stability was also observed in emulsions containing phenylethanol, m-cresol and …
Partitioning of parabens between phases of submicron emulsions stabilized with egg lecithin.
Watrobska-Swietlikowska D, Sznitowska M. Watrobska-Swietlikowska D, et al. Int J Pharm. 2006 Apr 7;312(1-2):174-8. doi: 10.1016/j.ijpharm.2006.01.005. Epub 2006 Feb 10. Int J Pharm. 2006. PMID: 16472951
Partitioning of methyl and propyl parabens (methyl and propyl hydroxybenzoate, paraben M and P) between the major phases in the parenteral submicron emulsions was studied. ...Depending on the formulation, Fw was 17-31% and 2.3-6.0% for paraben M and P, respectively. …
Partitioning of methyl and propyl parabens (methyl and propyl hydroxybenzoate, paraben M and P) between the major phases in the paren …
11 results