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1880 1
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2011 1
2013 1
2015 1
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2020 4
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2023 3
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Page 1
Dexamethasone in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. N Engl J Med. 2021. PMID: 32678530 Free PMC article. Clinical Trial.
Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Mafham M, Linsell L, Bell JL, Staplin N, Emberson JR, Wiselka M, Ustianowski A, Elmahi E, Prudon B, Whitehouse T, Felton T, Williams J, Faccenda J, Underwood J, Baillie JK, Chappell LC, Faust SN, Jaki T, Jeffery K, Lim WS, Montgomery A, Rowan K, Tarning J, Watson JA, White NJ, Juszczak E, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2020 Nov 19;383(21):2030-2040. doi: 10.1056/NEJMoa2022926. Epub 2020 Oct 8. N Engl J Med. 2020. PMID: 33031652 Free PMC article. Clinical Trial.
Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.
Abud AA, Abi B, Acciarri R, Acero MA, Adames MR, Adamov G, Adamowski M, Adams D, Adinolfi M, Aduszkiewicz A, Aguilar J, Ahmad Z, Ahmed J, Aimard B, Ali-Mohammadzadeh B, Alion T, Allison K, Monsalve SA, AlRashed M, Alt C, Alton A, Alvarez R, Amedo P, Anderson J, Andreopoulos C, Andreotti M, Andrews M, Andrianala F, Andringa S, Anfimov N, Ankowski A, Antoniassi M, Antonova M, Antoshkin A, Antusch S, Aranda-Fernandez A, Arellano L, Arnold LO, Arroyave MA, Asaadi J, Asquith L, Aurisano A, Aushev V, Autiero D, Lara VA, Ayala-Torres M, Azfar F, Back A, Back H, Back JJ, Backhouse C, Bagaturia I, Bagby L, Balashov N, Balasubramanian S, Baldi P, Baller B, Bambah B, Barao F, Barenboim G, Alzas PB, Barker G, Barkhouse W, Barnes C, Barr G, Monarca JB, Barros A, Barros N, Barrow JL, Basharina-Freshville A, Bashyal A, Basque V, Batchelor C, Chagas EBD, Battat JBR, Battisti F, Bay F, Bazetto MCQ, Alba JLLB, Beacom JF, Bechetoille E, Behera B, Beigbeder C, Bellantoni L, Bellettini G, Bellini V, Beltramello O, Benekos N, Montiel CB, Neves FB, Berger J, Berkman S, Bernardini P, Berner RM, Bersani A, Bertolucci S, Betancourt M, Rodríguez AB, Bevan A, Bezawada Y, Bezerra TJC, Bhardwaj A, Bhatnagar V,… See abstract for full author list ➔ Abud AA, et al. Eur Phys J C Part Fields. 2022;82(7):618. doi: 10.1140/epjc/s10052-022-10549-w. Epub 2022 Jul 16. Eur Phys J C Part Fields. 2022. PMID: 35859696 Free PMC article.
DUNE is a dual-site experiment for long-baseline neutrino oscillation studies, neutrino astrophysics and nucleon decay searches. ProtoDUNE Dual Phase (DP) is a 6 6 6 m 3 liquid argon time-projection-chamber (LArTPC) that recorded cosmic-muon data at the CERN Neutrino Platf …
DUNE is a dual-site experiment for long-baseline neutrino oscillation studies, neutrino astrophysics and nucleon decay searches. ProtoDUNE D …
The antagonistic transcription factors, EspM and EspN, regulate the ESX-1 secretion system in M. marinum.
Nicholson KR, Cronin RM, Prest RJ, Menon AR, Yang Y, Jennisch MK, Champion MM, Tobin DM, Champion PA. Nicholson KR, et al. mBio. 2024 Apr 10;15(4):e0335723. doi: 10.1128/mbio.03357-23. Epub 2024 Mar 6. mBio. 2024. PMID: 38445877 Free PMC article.
However, deleting the espM or whiB6 gene does not phenocopy the deletion of the ESX-1 substrate genes during macrophage infection by M. marinum. In this study, we identified EspN, a critical transcription factor whose activity is masked by the EspM repressor under laborato …
However, deleting the espM or whiB6 gene does not phenocopy the deletion of the ESX-1 substrate genes during macrophage infection by M …
Functional Analysis of EspM, an ESX-1-Associated Transcription Factor in Mycobacterium marinum.
Sanchez KG, Prest RJ, Nicholson KR, Korotkov KV, Champion PA. Sanchez KG, et al. J Bacteriol. 2022 Dec 20;204(12):e0023322. doi: 10.1128/jb.00233-22. Epub 2022 Nov 30. J Bacteriol. 2022. PMID: 36448785 Free PMC article.
The screen yielded four EspM variants of interest, which we tested for activity in M. marinum. Our study revealed that the two helix-turn-helix domains are functionally distinct. ...
The screen yielded four EspM variants of interest, which we tested for activity in M. marinum. Our study revealed that the two helix- …
Does a bout of strength training affect 2,000 m rowing ergometer performance and rowing-specific maximal power 24 h later?
Gee TI, French DN, Howatson G, Payton SJ, Berger NJ, Thompson KG. Gee TI, et al. Eur J Appl Physiol. 2011 Nov;111(11):2653-62. doi: 10.1007/s00421-011-1878-3. Epub 2011 Mar 10. Eur J Appl Physiol. 2011. PMID: 21390543 Clinical Trial.
This study evaluated the impact of a bout of high-intensity strength training on 2,000 m rowing ergometer performance and rowing-specific maximal power. ...The 2,000 m test was repeated at 24 and 48 h post-ST, in addition SSJ, CMJ and PS tests were performed at thes …
This study evaluated the impact of a bout of high-intensity strength training on 2,000 m rowing ergometer performance and rowing-spec …
Catalytic mechanism of ancestral L-lysine oxidase assigned by sequence data mining.
Sugiura S, Nakano S, Niwa M, Hasebe F, Matsui D, Ito S. Sugiura S, et al. J Biol Chem. 2021 Sep;297(3):101043. doi: 10.1016/j.jbc.2021.101043. Epub 2021 Aug 4. J Biol Chem. 2021. PMID: 34358565 Free PMC article.
R76A and E383D variants were also observed to lose their activity, and the k(cat)/K(m) value of G251P and Y253A mutations were approximately 800- to 1800-fold lower than that of AncLLysO, despite the indirect interaction of the substrates with the mutated residues. ...
R76A and E383D variants were also observed to lose their activity, and the k(cat)/K(m) value of G251P and Y253A mutations were approx …
Influence of Temperature on Growth of Four Different Opportunistic Pathogens in Drinking Water Biofilms.
van der Wielen PWJJ, Dignum M, Donocik A, Prest EI. van der Wielen PWJJ, et al. Microorganisms. 2023 Jun 14;11(6):1574. doi: 10.3390/microorganisms11061574. Microorganisms. 2023. PMID: 37375076 Free PMC article.
Our results reveal that the growth of P. aeruginosa and S. maltophilia in the biofilm already occurred at 15.0 C, whereas M. kansasii and A. fumigatus were able to grow when temperatures were above 20.0 C and 25.0 C, respectively. Moreover, the maximum growth yield of P. a …
Our results reveal that the growth of P. aeruginosa and S. maltophilia in the biofilm already occurred at 15.0 C, whereas M. kansasii …
Partial Consensus Design and Enhancement of Protein Function by Secondary-Structure-Guided Consensus Mutations.
Kozuka K, Nakano S, Asano Y, Ito S. Kozuka K, et al. Biochemistry. 2021 Jul 27;60(29):2309-2319. doi: 10.1021/acs.biochem.1c00309. Epub 2021 Jul 13. Biochemistry. 2021. PMID: 34254784
Structural and functional analysis of PcTDHs suggested that thermostability would be independently improved when consensus mutations are introduced into the loop region of TDHs. On the other hand, enzyme kinetic parameters (k(cat)/K(m)) and average productivity would be sy …
Structural and functional analysis of PcTDHs suggested that thermostability would be independently improved when consensus mutations are int …
30 results