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Year Number of Results
2005 2
2006 2
2009 2
2017 1
2018 4
2019 2
2020 4
2021 2
2022 2
2023 2
2024 0

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Page 1
Advances in Protein Degradation.
Castaldi MP, Fisher SL. Castaldi MP, et al. SLAS Discov. 2021 Apr;26(4):471-473. doi: 10.1177/24725552211001823. SLAS Discov. 2021. PMID: 33780295 Free article. No abstract available.
Proteolysis-targeting chimeras in drug development: A safety perspective.
Moreau K, Coen M, Zhang AX, Pachl F, Castaldi MP, Dahl G, Boyd H, Scott C, Newham P. Moreau K, et al. Among authors: castaldi mp. Br J Pharmacol. 2020 Apr;177(8):1709-1718. doi: 10.1111/bph.15014. Epub 2020 Feb 25. Br J Pharmacol. 2020. PMID: 32022252 Free PMC article. Review.
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.
Wrobel L, Hill SM, Djajadikerta A, Fernandez-Estevez M, Karabiyik C, Ashkenazi A, Barratt VJ, Stamatakou E, Gunnarsson A, Rasmusson T, Miele EW, Beaton N, Bruderer R, Feng Y, Reiter L, Castaldi MP, Jarvis R, Tan K, Bürli RW, Rubinsztein DC. Wrobel L, et al. Among authors: castaldi mp. Nat Commun. 2022 Jul 16;13(1):4146. doi: 10.1038/s41467-022-31905-0. Nat Commun. 2022. PMID: 35842429 Free PMC article.
Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners.
Doshi AS, Cantin S, Hernandez M, Srinivasan S, Tentarelli S, Griffin M, Wang Y, Pop-Damkov P, Prickett LB, Kankkonen C, Shen M, Martin MS, Wu S, Castaldi MP, Ghadially H, Varnes J, Gales S, Henry D, Hoover C, Mele DA, Simpson I, Gangl ET, Mlynarski SN, Finlay MRV, Drew L, Fawell SE, Shao W, Schuller AG. Doshi AS, et al. Among authors: castaldi mp. Mol Cancer Ther. 2023 May 4;22(5):630-645. doi: 10.1158/1535-7163.MCT-22-0431. Mol Cancer Ther. 2023. PMID: 36912782
Mechanistic Insights into a CDK9 Inhibitor Via Orthogonal Proteomics Methods.
Hendricks JA, Beaton N, Chernobrovkin A, Miele E, Hamza GM, Ricchiuto P, Tomlinson RC, Friman T, Borenstain C, Barlaam B, Hande S, Lamb ML, De Savi C, Davies R, Main M, Hellner J, Beeler K, Feng Y, Bruderer R, Reiter L, Molina DM, Castaldi MP. Hendricks JA, et al. Among authors: castaldi mp. ACS Chem Biol. 2022 Jan 21;17(1):54-67. doi: 10.1021/acschembio.1c00488. Epub 2021 Dec 25. ACS Chem Biol. 2022. PMID: 34955012 Free article.
EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex.
Hsu JH, Rasmusson T, Robinson J, Pachl F, Read J, Kawatkar S, O' Donovan DH, Bagal S, Code E, Rawlins P, Argyrou A, Tomlinson R, Gao N, Zhu X, Chiarparin E, Jacques K, Shen M, Woods H, Bednarski E, Wilson DM, Drew L, Castaldi MP, Fawell S, Bloecher A. Hsu JH, et al. Among authors: castaldi mp. Cell Chem Biol. 2020 Jan 16;27(1):41-46.e17. doi: 10.1016/j.chembiol.2019.11.004. Epub 2019 Nov 27. Cell Chem Biol. 2020. PMID: 31786184 Free article.
21 results