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Page 1
Simple versus Radical Hysterectomy in Women with Low-Risk Cervical Cancer.
Plante M, Kwon JS, Ferguson S, Samouëlian V, Ferron G, Maulard A, de Kroon C, Van Driel W, Tidy J, Williamson K, Mahner S, Kommoss S, Goffin F, Tamussino K, Eyjólfsdóttir B, Kim JW, Gleeson N, Brotto L, Tu D, Shepherd LE; CX.5 SHAPE investigators; CX.5 SHAPE Investigators. Plante M, et al. N Engl J Med. 2024 Feb 29;390(9):819-829. doi: 10.1056/NEJMoa2308900. N Engl J Med. 2024. PMID: 38416430 Free article. Clinical Trial.
The incidence of urinary incontinence was lower in the simple hysterectomy group than in the radical hysterectomy group within 4 weeks after surgery (2.4% vs. 5.5%; P = 0.048) and beyond 4 weeks (4.7% vs. 11.0%; P = 0.003). The incidence of urinary retention in the …
The incidence of urinary incontinence was lower in the simple hysterectomy group than in the radical hysterectomy group within 4 weeks after …
Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency.
Block J, Rashkova C, Castanon I, Zoghi S, Platon J, Ardy RC, Fujiwara M, Chaves B, Schoppmeyer R, van der Made CI, Jimenez Heredia R, Harms FL, Alavi S, Alsina L, Sanchez Moreno P, Ávila Polo R, Cabrera-Pérez R, Kostel Bal S, Pfajfer L, Ransmayr B, Mautner AK, Kondo R, Tinnacher A, Caldera M, Schuster M, Domínguez Conde C, Platzer R, Salzer E, Boyer T, Brunner HG, Nooitgedagt-Frons JE, Iglesias E, Deyà-Martinez A, Camacho-Lovillo M, Menche J, Bock C, Huppa JB, Pickl WF, Distel M, Yoder JA, Traver D, Engelhardt KR, Linden T, Kager L, Hannich JT, Hoischen A, Hambleton S, Illsinger S, Da Costa L, Kutsche K, Chavoshzadeh Z, van Buul JD, Antón J, Calzada-Hernández J, Neth O, Viaud J, Nishikimi A, Dupré L, Boztug K. Block J, et al. N Engl J Med. 2023 Aug 10;389(6):527-539. doi: 10.1056/NEJMoa2210054. Epub 2023 Jun 21. N Engl J Med. 2023. PMID: 37342957
TGFB1 induces fetal reprogramming and enhances intestinal regeneration.
Chen L, Qiu X, Dupre A, Pellon-Cardenas O, Fan X, Xu X, Rout P, Walton KD, Burclaff J, Zhang R, Fang W, Ofer R, Logerfo A, Vemuri K, Bandyopadhyay S, Wang J, Barbet G, Wang Y, Gao N, Perekatt AO, Hu W, Magness ST, Spence JR, Verzi MP. Chen L, et al. Cell Stem Cell. 2023 Nov 2;30(11):1520-1537.e8. doi: 10.1016/j.stem.2023.09.015. Epub 2023 Oct 20. Cell Stem Cell. 2023. PMID: 37865088
Aflibercept Monotherapy or Bevacizumab First for Diabetic Macular Edema.
Jhaveri CD, Glassman AR, Ferris FL 3rd, Liu D, Maguire MG, Allen JB, Baker CW, Browning D, Cunningham MA, Friedman SM, Jampol LM, Marcus DM, Martin DF, Preston CM, Stockdale CR, Sun JK; DRCR Retina Network. Jhaveri CD, et al. N Engl J Med. 2022 Aug 25;387(8):692-703. doi: 10.1056/NEJMoa2204225. Epub 2022 Jul 14. N Engl J Med. 2022. PMID: 35833805 Free PMC article. Clinical Trial.
The mean improvement in visual acuity was 15.0 letters in the aflibercept-monotherapy group and 14.0 letters in the bevacizumab-first group (adjusted difference, 0.8 letters; 95% confidence interval, -0.9 to 2.5; P = 0.37). At 2 years, the mean changes in visual acuity and …
The mean improvement in visual acuity was 15.0 letters in the aflibercept-monotherapy group and 14.0 letters in the bevacizumab-first group …
Adherence to ESGO guidelines and impact on survival in obese patients with endometrial cancer: a multicentric retrospective study.
Ouasti S, Ilic J, Mimoun C, Bendifallah S, Huchon C, Ouldamer L, Lorenzini J, Lavoué V, Raimond E, Dion L, Costaz H, Dupre PF, Graesslin O, Uzan J, Kerbage Y, Chauvet P, Canlorbe G, Touboul C, Dabi Y. Ouasti S, et al. Int J Gynecol Cancer. 2023 Dec 4;33(12):1950-1956. doi: 10.1136/ijgc-2023-004642. Int J Gynecol Cancer. 2023. PMID: 37788899 Review.
The surgical management of the morbid group was in accordance with the guidelines in only 30% of cases, compared with 44% for the obese group and 48% for the normal or overweight group (p<0.001); this was largely because of a lack of lymph node staging. Morbid group pat …
The surgical management of the morbid group was in accordance with the guidelines in only 30% of cases, compared with 44% for the obese grou …
First Measurement of Timelike Compton Scattering.
Chatagnon P, Niccolai S, Stepanyan S, Amaryan MJ, Angelini G, Armstrong WR, Atac H, Ayerbe Gayoso C, Baltzell NA, Barion L, Bashkanov M, Battaglieri M, Bedlinskiy I, Benmokhtar F, Bianconi A, Biondo L, Biselli AS, Bondi M, Bossù F, Boiarinov S, Briscoe WJ, Brooks WK, Bulumulla D, Burkert VD, Carman DS, Carvajal JC, Caudron M, Celentano A, Chetry T, Ciullo G, Clark L, Cole PL, Contalbrigo M, Costantini G, Crede V, D'Angelo A, Dashyan N, Defurne M, De Vita R, Deur A, Diehl S, Djalali C, Dupré R, Egiyan H, Ehrhart M, El Alaoui A, El Fassi L, Elouadrhiri L, Fegan S, Fersch R, Filippi A, Gavalian G, Ghandilyan Y, Gilfoyle GP, Girod FX, Glazier DI, Golubenko AA, Gothe RW, Gotra Y, Griffioen KA, Guidal M, Guo L, Hakobyan H, Hattawy M, Hayward TB, Heddle D, Hobart A, Holtrop M, Hyde CE, Ilieva Y, Ireland DG, Isupov EL, Jo HS, Joo K, Kabir ML, Keller D, Khachatryan G, Khanal A, Kim A, Kim W, Kripko A, Kubarovsky V, Kuhn SE, Lanza L, Leali M, Lee S, Lenisa P, Livingston K, MacGregor IJD, Marchand D, Marsicano L, Mascagna V, McKinnon B, McLauchlin C, Migliorati S, Mirazita M, Mokeev V, Montgomery RA, Munoz Camacho C, Nadel-Turonski P, Naidoo P, Neupane K, O'Connell TR, Osipenko M, Ouillon M,… See abstract for full author list ➔ Chatagnon P, et al. Phys Rev Lett. 2021 Dec 24;127(26):262501. doi: 10.1103/PhysRevLett.127.262501. Phys Rev Lett. 2021. PMID: 35029502 Free article.
Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.
Dupre TV, Doll MA, Shah PP, Sharp CN, Siow D, Megyesi J, Shayman J, Bielawska A, Bielawski J, Beverly LJ, Hernandez-Corbacho M, Clarke CJ, Snider AJ, Schnellmann RG, Obeid LM, Hannun YA, Siskind LJ. Dupre TV, et al. J Lipid Res. 2017 Jul;58(7):1439-1452. doi: 10.1194/jlr.M076745. Epub 2017 May 10. J Lipid Res. 2017. PMID: 28490444 Free PMC article.
Under conditions of high ceramide generation, data suggest that metabolism of ceramides to glucosylceramides buffers kidney ceramides and helps attenuate kidney injury.-Dupre, T. V., M. A. Doll, P. P. Shah, C. N. Sharp, D. Siow, J. Megyesi, J. Shayman, …
Under conditions of high ceramide generation, data suggest that metabolism of ceramides to glucosylceramides buffers kidney ceramides and he …
Facility-Level Factors and Racial Disparities in Cardiopulmonary Resuscitation within US Dialysis Clinics.
Pun PH, Svetkey LP, McNally B, Dupre ME; CARES Surveillance Group. Pun PH, et al. Kidney360. 2022 Mar 11;3(6):1021-1030. doi: 10.34067/KID.0008092021. eCollection 2022 Jun 30. Kidney360. 2022. PMID: 35845342 Free PMC article.
RESULTS: Compared with White patients, Black cardiac arrest patients dialyzed in larger facilities (26 versus 21 dialysis stations; P<0.001), facilities with fewer registered nurses per station (0.29 versus 0.33; P<0.001), and facilities with lower quality sco …
RESULTS: Compared with White patients, Black cardiac arrest patients dialyzed in larger facilities (26 versus 21 dialysis stations; P
Moyamoya Disease Susceptibility Gene RNF213 Regulates Endothelial Barrier Function.
Roy V, Ross JP, Pépin R, Cortez Ghio S, Brodeur A, Touzel Deschênes L, Le-Bel G, Phillips DE, Milot G, Dion PA, Guérin S, Germain L, Berthod F, Auger FA, Rouleau GA, Dupré N, Gros-Louis F. Roy V, et al. Stroke. 2022 Apr;53(4):1263-1275. doi: 10.1161/STROKEAHA.120.032691. Epub 2022 Jan 7. Stroke. 2022. PMID: 34991336
Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry.
Strangfeld A, Schäfer M, Gianfrancesco MA, Lawson-Tovey S, Liew JW, Ljung L, Mateus EF, Richez C, Santos MJ, Schmajuk G, Scirè CA, Sirotich E, Sparks JA, Sufka P, Thomas T, Trupin L, Wallace ZS, Al-Adely S, Bachiller-Corral J, Bhana S, Cacoub P, Carmona L, Costello R, Costello W, Gossec L, Grainger R, Hachulla E, Hasseli R, Hausmann JS, Hyrich KL, Izadi Z, Jacobsohn L, Katz P, Kearsley-Fleet L, Robinson PC, Yazdany J, Machado PM; COVID-19 Global Rheumatology Alliance. Strangfeld A, et al. Ann Rheum Dis. 2021 Jul;80(7):930-942. doi: 10.1136/annrheumdis-2020-219498. Epub 2021 Jan 27. Ann Rheum Dis. 2021. PMID: 33504483 Free PMC article.
55 results