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Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection.
Ahuja SK, Manoharan MS, Lee GC, McKinnon LR, Meunier JA, Steri M, Harper N, Fiorillo E, Smith AM, Restrepo MI, Branum AP, Bottomley MJ, Orrù V, Jimenez F, Carrillo A, Pandranki L, Winter CA, Winter LA, Gaitan AA, Moreira AG, Walter EA, Silvestri G, King CL, Zheng YT, Zheng HY, Kimani J, Blake Ball T, Plummer FA, Fowke KR, Harden PN, Wood KJ, Ferris MT, Lund JM, Heise MT, Garrett N, Canady KR, Abdool Karim SS, Little SJ, Gianella S, Smith DM, Letendre S, Richman DD, Cucca F, Trinh H, Sanchez-Reilly S, Hecht JM, Cadena Zuluaga JA, Anzueto A, Pugh JA; South Texas Veterans Health Care System COVID-19 team; Agan BK, Root-Bernstein R, Clark RA, Okulicz JF, He W. Ahuja SK, et al. Nat Commun. 2023 Jun 13;14(1):3286. doi: 10.1038/s41467-023-38238-6. Nat Commun. 2023. PMID: 37311745 Free PMC article.
Immunologic resilience and COVID-19 survival advantage.
Lee GC, Restrepo MI, Harper N, Manoharan MS, Smith AM, Meunier JA, Sanchez-Reilly S, Ehsan A, Branum AP, Winter C, Winter L, Jimenez F, Pandranki L, Carrillo A, Perez GL, Anzueto A, Trinh H, Lee M, Hecht JM, Martinez-Vargas C, Sehgal RT, Cadena J, Walter EA, Oakman K, Benavides R, Pugh JA; South Texas Veterans Health Care System COVID-19 Team; Letendre S, Steri M, Orrù V, Fiorillo E, Cucca F, Moreira AG, Zhang N, Leadbetter E, Agan BK, Richman DD, He W, Clark RA, Okulicz JF, Ahuja SK. Lee GC, et al. J Allergy Clin Immunol. 2021 Nov;148(5):1176-1191. doi: 10.1016/j.jaci.2021.08.021. Epub 2021 Sep 8. J Allergy Clin Immunol. 2021. PMID: 34508765 Free PMC article.
Miniaturized FDDA and CMOS Based Potentiostat for Bio-Applications.
Ghodsevali E, Morneau-Gamache S, Mathault J, Landari H, Boisselier É, Boukadoum M, Gosselin B, Miled A. Ghodsevali E, et al. Sensors (Basel). 2017 Apr 10;17(4):810. doi: 10.3390/s17040810. Sensors (Basel). 2017. PMID: 28394289 Free PMC article.
The FDDA also reduces the number of amplifiers and passive elements in the potentiostat design, which lowers the overall power consumption and noise. The proposed potentiostat was fabricated in 0.18 m CMOS, with 1.8 V supply voltage. The device achieved 5 A sensitivity and …
The FDDA also reduces the number of amplifiers and passive elements in the potentiostat design, which lowers the overall power consumption a …
Harmonised statistics and maps of forest biomass and increment in Europe.
Avitabile V, Pilli R, Migliavacca M, Duveiller G, Camia A, Blujdea V, Adolt R, Alberdi I, Barreiro S, Bender S, Borota D, Bosela M, Bouriaud O, Breidenbach J, Cañellas I, Čavlović J, Colin A, Di Cosmo L, Donis J, Fischer C, Freudenschuss A, Fridman J, Gasparini P, Gschwantner T, Hernández L, Korhonen K, Kulbokas G, Kvist V, Latte N, Lazdins A, Lejeune P, Makovskis K, Marin G, Maslo J, Michorczyk A, Mionskowski M, Morneau F, Myszkowski M, Nagy K, Nilsson M, Nord-Larsen T, Pantic D, Perin J, Redmond J, Rizzo M, Šebeň V, Skudnik M, Snorrason A, Sroga R, Stoyanov T, Svensson A, Talarczyk A, Teeuwen S, Thürig E, Uva J, Mubareka S. Avitabile V, et al. Sci Data. 2024 Mar 6;11(1):274. doi: 10.1038/s41597-023-02868-8. Sci Data. 2024. PMID: 38448454 Free PMC article.
The maps are coherent with the statistics and depict the spatial distribution of the forest variables at 100 m resolution....
The maps are coherent with the statistics and depict the spatial distribution of the forest variables at 100 m resolution....
Spectral characterization of flash and high flux x-ray radiographic sources with a magnetic Compton spectrometer.
Espy M, Klasky M, James M, Moir D, Mendez J, Morneau R, Shurter R, Sedillo R, Volegov P, Gehring A. Espy M, et al. Rev Sci Instrum. 2021 Aug 1;92(8):083102. doi: 10.1063/5.0053184. Rev Sci Instrum. 2021. PMID: 34470406
We present an application of this method to data from a nominal 19.4 MeV flash radiographic source (the first axis of the Dual Axis Radiographic Hydro-Test Facility) capable of generating 500 R @ 1 m in 60 ns and a medical therapy source (a Scanditronix M22, Microtron) cap …
We present an application of this method to data from a nominal 19.4 MeV flash radiographic source (the first axis of the Dual Axis Radiogra …
Development of a continuous assay and steady-state characterization of Escherichia coli threonine synthase.
Morneau DJ, Abouassaf E, Skanes JE, Aitken SM. Morneau DJ, et al. Anal Biochem. 2012 Apr 1;423(1):78-85. doi: 10.1016/j.ab.2012.01.004. Epub 2012 Jan 18. Anal Biochem. 2012. PMID: 22289691
To validate this assay, TS from E. coli was characterized. The kinetic parameters (k(cat)=4s(-1) and K(m)=0.34 mM) and the pH optimum of 8.7, determined using the continuous assay, are consistent with values reported for this enzyme based on the discontinuous malachite gre …
To validate this assay, TS from E. coli was characterized. The kinetic parameters (k(cat)=4s(-1) and K(m)=0.34 mM) and the pH optimum …
An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12.
Keasar C, McGuffin LJ, Wallner B, Chopra G, Adhikari B, Bhattacharya D, Blake L, Bortot LO, Cao R, Dhanasekaran BK, Dimas I, Faccioli RA, Faraggi E, Ganzynkowicz R, Ghosh S, Ghosh S, Giełdoń A, Golon L, He Y, Heo L, Hou J, Khan M, Khatib F, Khoury GA, Kieslich C, Kim DE, Krupa P, Lee GR, Li H, Li J, Lipska A, Liwo A, Maghrabi AHA, Mirdita M, Mirzaei S, Mozolewska MA, Onel M, Ovchinnikov S, Shah A, Shah U, Sidi T, Sieradzan AK, Ślusarz M, Ślusarz R, Smadbeck J, Tamamis P, Trieber N, Wirecki T, Yin Y, Zhang Y, Bacardit J, Baranowski M, Chapman N, Cooper S, Defelicibus A, Flatten J, Koepnick B, Popović Z, Zaborowski B, Baker D, Cheng J, Czaplewski C, Delbem ACB, Floudas C, Kloczkowski A, Ołdziej S, Levitt M, Scheraga H, Seok C, Söding J, Vishveshwara S, Xu D; Foldit Players consortium; Crivelli SN. Keasar C, et al. Sci Rep. 2018 Jul 2;8(1):9939. doi: 10.1038/s41598-018-26812-8. Sci Rep. 2018. PMID: 29967418 Free PMC article.
The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: a double-blind randomized crossover clinical trial.
Liet JM, Pelletier V, Robinson BH, Laryea MD, Wendel U, Morneau S, Morin C, Mitchell G, Lacroix J. Liet JM, et al. J Pediatr. 2003 Jan;142(1):62-6. doi: 10.1067/mpd.2003.mpd0333. J Pediatr. 2003. PMID: 12520257 Clinical Trial.
Mean VO(2) was lower after administration of either DMG (-1 +/- 3 mL x min(-1) x m(-2)) or placebo (-6 +/- 4), but neither difference was statistically significant. There was no detectable effect of DMG treatment on blood levels of lactate, pyruvate, bicarbonate, or pH. VO …
Mean VO(2) was lower after administration of either DMG (-1 +/- 3 mL x min(-1) x m(-2)) or placebo (-6 +/- 4), but neither difference …
Seasonal water stress tolerance and habitat associations within four neotropical tree genera.
Baraloto C, Morneau F, Bonal D, Blanc L, Ferry B. Baraloto C, et al. Ecology. 2007 Feb;88(2):478-89. doi: 10.1890/0012-9658(2007)88[478:swstah]2.0.co;2. Ecology. 2007. PMID: 17479765
We analyzed 10-year data sets of mapped and measured saplings (stems >150 cm in height and <10 cm diameter at breast height [dbh]) and trees (stems > or =10 cm dbh) across 37.5 ha of permanent plots covering a 300-ha zone, within which seasonally flooded areas (where the …
We analyzed 10-year data sets of mapped and measured saplings (stems >150 cm in height and <10 cm diameter at breast height [dbh]) and …
11 results