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Cancer cells relax and resist cytotoxic attack.
Usmani SM, Mempel TR. Usmani SM, et al. Immunity. 2021 May 11;54(5):853-855. doi: 10.1016/j.immuni.2021.04.017. Immunity. 2021. PMID: 33979583 Free article.
When it comes to cancer evading the immune response, antigen presentation usually gets all the attention. In this issue of Immunity, Tello-Lafoz et al. reveal that cancer cells have another card up their sleeve: by regulating gene expression to "soften" their actin cytoske …
When it comes to cancer evading the immune response, antigen presentation usually gets all the attention. In this issue of Immunity, Tello- …
Analysis of Mycobacterium africanum in the last 17 years in Aragon identifies a specific location of IS6110 in Lineage 6.
Comín J, Monforte ML, Samper S; Aragonese Working Group on Molecular Epidemiology of Tuberculosis (EPIMOLA); Otal I. Comín J, et al. Sci Rep. 2021 May 14;11(1):10359. doi: 10.1038/s41598-021-89511-x. Sci Rep. 2021. PMID: 33990628 Free PMC article.
The study includes all the cases in our region, where all the M. tuberculosis complex isolates are systematically characterised. We detected 31 cases of M. africanum among 2598 cases of TB in the period studied. TB caused by M. africanum is rare (1.19%) in ou …
The study includes all the cases in our region, where all the M. tuberculosis complex isolates are systematically characterised. We d …
Molecular Characterization of Mycobacterium tuberculosis Strains with TB-SPRINT.
Molina-Moya B, Gomgnimbou MK, Lafoz C, Lacoma A, Prat C, Refrégier G, Samper S, Dominguez J, Sola C. Molina-Moya B, et al. Am J Trop Med Hyg. 2017 Sep;97(3):806-809. doi: 10.4269/ajtmh.16-0782. Epub 2017 Jul 19. Am J Trop Med Hyg. 2017. PMID: 28722603 Free PMC article.
We evaluated Tuberculosis-Spoligo-Rifampicin-Isoniazid Typing (TB-SPRINT), a microbead-based method for spoligotyping and detection of rifampicin and isoniazid resistance in Mycobacterium tuberculosis. For that, 67 M. tuberculosis complex strains were retrospectively selec …
We evaluated Tuberculosis-Spoligo-Rifampicin-Isoniazid Typing (TB-SPRINT), a microbead-based method for spoligotyping and detection of rifam …
Extended safety studies of the attenuated live tuberculosis vaccine SO2 based on phoP mutant.
Cardona PJ, Asensio JG, Arbués A, Otal I, Lafoz C, Gil O, Caceres N, Ausina V, Gicquel B, Martin C. Cardona PJ, et al. Vaccine. 2009 Apr 21;27(18):2499-505. doi: 10.1016/j.vaccine.2009.02.060. Epub 2009 Feb 24. Vaccine. 2009. PMID: 19368792
Studies in a post-exposure model of guinea pigs and mice, previously infected with M. tuberculosis, were performed and no toxicity effects were found after inoculation of SO2. ...
Studies in a post-exposure model of guinea pigs and mice, previously infected with M. tuberculosis, were performed and no toxicity ef …
Epidemiological evidence of the spread of a Mycobacterium tuberculosis strain of the Beijing genotype on Gran Canaria Island.
Caminero JA, Pena MJ, Campos-Herrero MI, Rodríguez JC, García I, Cabrera P, Lafoz C, Samper S, Takiff H, Afonso O, Pavón JM, Torres MJ, van Soolingen D, Enarson DA, Martin C. Caminero JA, et al. Am J Respir Crit Care Med. 2001 Oct 1;164(7):1165-70. doi: 10.1164/ajrccm.164.7.2101031. Am J Respir Crit Care Med. 2001. PMID: 11673204
IS6110 restriction fragment length polymorphism (RFLP) analysis was performed on M. tuberculosis isolates from 566 of the 721 patients (78.5%) diagnosed with tuberculosis (TB) on Gran Canaria Island from 1993 to 1996, as well as 35% of isolates from 1991-1992 (85 strains). …
IS6110 restriction fragment length polymorphism (RFLP) analysis was performed on M. tuberculosis isolates from 566 of the 721 patient …
Molecular characterisation of Mycobacterium tuberculosis isolates in the First National Survey of Anti-tuberculosis Drug Resistance from Venezuela.
Aristimuño L, Armengol R, Cebollada A, España M, Guilarte A, Lafoz C, Lezcano MA, Revillo MJ, Martín C, Ramírez C, Rastogi N, Rojas J, de Salas AV, Sola C, Samper S. Aristimuño L, et al. BMC Microbiol. 2006 Oct 10;6:90. doi: 10.1186/1471-2180-6-90. BMC Microbiol. 2006. PMID: 17032442 Free PMC article.
BACKGROUND: Molecular typing of Mycobacterium tuberculosis strains has become a valuable tool in the epidemiology of tuberculosis (TB) by allowing detection of outbreaks, tracking of epidemics, identification of genotypes and transmission events among patients who would have rema …
BACKGROUND: Molecular typing of Mycobacterium tuberculosis strains has become a valuable tool in the epidemiology of tuberculosis (TB) by al …
Genotyping of Mycobacterium tuberculosis over two periods: a changing scenario for tuberculosis transmission.
López-Calleja AI, Lezcano MA, Vitoria MA, Iglesias MJ, Cebollada A, Lafoz C, Gavin P, Aristimuño L, Revillo MJ, Martin C, Samper S. López-Calleja AI, et al. Int J Tuberc Lung Dis. 2007 Oct;11(10):1080-6. Int J Tuberc Lung Dis. 2007. PMID: 17945064
The main differences with the previous study were the increase of TB cases among immigrants, a decrease in HIV-TB co-infected patients and the occurrence of a large TB outbreak involving 85 patients (M. tuberculosis Zaragoza [MTZ] strain). CONCLUSION: A change in the epide …
The main differences with the previous study were the increase of TB cases among immigrants, a decrease in HIV-TB co-infected patients and t …