Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2015 1
2016 2
2020 1
2021 1
2022 1
2023 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

6 results

Results by year

Filters applied: . Clear all
Your search was processed without automatic term mapping because it retrieved zero results.
Page 1
Dammarane triterpenes targeting α-synuclein: biological activity and evaluation of binding sites by molecular docking.
Cornejo A, Caballero J, Simirgiotis M, Torres V, Sánchez L, Díaz N, Guimaraes M, Hernández M, Areche C, Alfaro S, Caballero L, Melo F. Cornejo A, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):154-162. doi: 10.1080/14756366.2020.1851216. J Enzyme Inhib Med Chem. 2021. PMID: 33307873 Free PMC article.
Since compound 1 was most active, we determined the interaction between alpha-synuclein and 1 at 50 M (Kd) through microscale thermophoresis. Also, we observed differences in height and diameter of aggregates, and alpha-synuclein remains unfolded in the presence of 1. ...
Since compound 1 was most active, we determined the interaction between alpha-synuclein and 1 at 50 M (Kd) through microscale thermop …
Antifungal activity of phytotherapeutic preparation of Baccharis species from argentine Puna against clinically relevant fungi.
Carrizo SL, Zampini IC, Sayago JE, Simirgiotis MJ, Bórquez J, Cuello AS, Isla MI. Carrizo SL, et al. J Ethnopharmacol. 2020 Apr 6;251:112553. doi: 10.1016/j.jep.2020.112553. Epub 2020 Jan 8. J Ethnopharmacol. 2020. PMID: 31923539
CONCLUSIONS: In this work the traditional use of both Baccharis species as an antimicrobial against commercial products resistant fungal strains was validate, principally against dermatophytes fungi such as T. rubrum, T. mentagrophytes, M. canis, and M. gypseum. The …
CONCLUSIONS: In this work the traditional use of both Baccharis species as an antimicrobial against commercial products resistant fungal str …
Secondary Metabolites in Ramalina terebrata Detected by UHPLC/ESI/MS/MS and Identification of Parietin as Tau Protein Inhibitor.
Cornejo A, Salgado F, Caballero J, Vargas R, Simirgiotis M, Areche C. Cornejo A, et al. Int J Mol Sci. 2016 Aug 18;17(8):1303. doi: 10.3390/ijms17081303. Int J Mol Sci. 2016. PMID: 27548142 Free PMC article.
All compounds showed null activity with the exception of parietin, which it was able to inhibit aggregation process of tau in a concentration range between 3 g/mL (10 M) to 28 g/mL (100 M). In addition, we show how parietin interact with tau (306)VQIVYK(311) hexapep …
All compounds showed null activity with the exception of parietin, which it was able to inhibit aggregation process of tau in a concentratio …
Isolation of cytotoxic diterpenoids from the Chilean medicinal plant Azorella compacta Phil from the Atacama Desert by high-speed counter-current chromatography.
Bórquez J, Bartolucci NL, Echiburú-Chau C, Winterhalter P, Vallejos J, Jerz G, Simirgiotis MJ. Bórquez J, et al. J Sci Food Agric. 2016 Jun;96(8):2832-8. doi: 10.1002/jsfa.7451. Epub 2015 Oct 1. J Sci Food Agric. 2016. PMID: 26425819
Besides, compounds 4, 6, 7, 8 and 11 displayed good cytotoxic activity (less than 50% cell viability at 100 M). Among them, compound 7, an acetylated azorellane, was the most active. ...
Besides, compounds 4, 6, 7, 8 and 11 displayed good cytotoxic activity (less than 50% cell viability at 100 M). Among them, compound …