Correlation of Body Weight and Composition With Hepatic Activities of Cytochrome P450 Enzymes.
Krogstad V, Peric A, Robertsen I, Kringen MK, Vistnes M, Hjelmesæth J, Sandbu R, Johnson LK, Angeles PC, Jansson-Löfmark R, Karlsson C, Andersson S, Åsberg A, Andersson TB, Christensen H.
Krogstad V, et al.
J Pharm Sci. 2021 Jan;110(1):432-437. doi: 10.1016/j.xphs.2020.10.027. Epub 2020 Oct 19.
J Pharm Sci. 2021.
PMID: 33091408
Free article.
Liver biopsies from 36 individuals with a body mass index (BMI) ranging from 18 to 63 kg/m(2) were obtained. Individual hepatic microsomes were prepared and activities of CYP3A, CYP2B6, CYP2C8, CYP2D6, CYP2C9, CYP2C19 and CYP1A2 were determined. ...
Liver biopsies from 36 individuals with a body mass index (BMI) ranging from 18 to 63 kg/m(2) were obtained. Individual hepatic micro …