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Year Number of Results
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2015 3
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2022 1
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Page 1
Natural products in drug discovery: advances and opportunities.
Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce; Supuran CT. Atanasov AG, et al. Nat Rev Drug Discov. 2021 Mar;20(3):200-216. doi: 10.1038/s41573-020-00114-z. Epub 2021 Jan 28. Nat Rev Drug Discov. 2021. PMID: 33510482 Free PMC article. Review.
Against all odds-the persistent popularity of homeopathy.
Cukaci C, Freissmuth M, Mann C, Marti J, Sperl V. Cukaci C, et al. Wien Klin Wochenschr. 2020 May;132(9-10):232-242. doi: 10.1007/s00508-020-01624-x. Epub 2020 Mar 9. Wien Klin Wochenschr. 2020. PMID: 32152694 Free PMC article. Review.
The conservative view: is it necessary to implant a stent into the dopamine transporter?
Schmid D, Koenig X, Bulusu S, Schicker K, Freissmuth M, Sitte HH, Sandtner W. Schmid D, et al. Br J Pharmacol. 2015 Oct;172(19):4775-8. doi: 10.1111/bph.12766. Br J Pharmacol. 2015. PMID: 24824446 Free PMC article.
Br J Pharmacol 172: this issue, doi: 10.1111/bph.12767, commenting on Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer FP, Boehm S, Freissmuth M and Sitte HH (2014). A quantitative model of amphetamine action on the 5-HT transporter. ...
Br J Pharmacol 172: this issue, doi: 10.1111/bph.12767, commenting on Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer FP, Bo …
A mechanism of uncompetitive inhibition of the serotonin transporter.
Bhat S, El-Kasaby A, Kasture A, Boytsov D, Reichelt JB, Hummel T, Sucic S, Pifl C, Freissmuth M, Sandtner W. Bhat S, et al. Elife. 2023 Jan 17;12:e82641. doi: 10.7554/eLife.82641. Elife. 2023. PMID: 36648438 Free PMC article.
Here, we explored the action of N-formyl-1,3-bis (3,4-methylenedioxyphenyl)-prop-2-yl-amine (ECSI#6) on SERT: inhibition of serotonin uptake by ECSI#6 was enhanced with increasing serotonin concentration. Conversely, the K(M) for serotonin was lowered by augmenting ECSI#6. …
Here, we explored the action of N-formyl-1,3-bis (3,4-methylenedioxyphenyl)-prop-2-yl-amine (ECSI#6) on SERT: inhibition of serotonin uptake …
Comments on 'A quantitative model of amphetamine action on the serotonin transporter', by Sandtner et al., Br J Pharmacol 171: 1007-1018.
De Felice LJ, Cameron KN. De Felice LJ, et al. Br J Pharmacol. 2015 Oct;172(19):4772-4. doi: 10.1111/bph.12767. Br J Pharmacol. 2015. PMID: 24824549 Free PMC article.
This article is a Commentary on Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer FP, Boehm S, Freissmuth M and Sitte HH (2014). A quantitative model of amphetamine action on the 5-HT transporter. ...
This article is a Commentary on Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer FP, Boehm S, Freissmuth M and …
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism.
Ng J, Barral S, De La Fuente Barrigon C, Lignani G, Erdem FA, Wallings R, Privolizzi R, Rossignoli G, Alrashidi H, Heasman S, Meyer E, Ngoh A, Pope S, Karda R, Perocheau D, Baruteau J, Suff N, Antinao Diaz J, Schorge S, Vowles J, Marshall LR, Cowley SA, Sucic S, Freissmuth M, Counsell JR, Wade-Martins R, Heales SJR, Rahim AA, Bencze M, Waddington SN, Kurian MA. Ng J, et al. Sci Transl Med. 2021 May 19;13(594):eaaw1564. doi: 10.1126/scitranslmed.aaw1564. Sci Transl Med. 2021. PMID: 34011628 Free PMC article.
Optimizing the Substrate Uptake Rate of Solute Carriers.
Schicker K, Farr CV, Boytsov D, Freissmuth M, Sandtner W. Schicker K, et al. Front Physiol. 2022 Feb 3;13:817886. doi: 10.3389/fphys.2022.817886. eCollection 2022. Front Physiol. 2022. PMID: 35185619 Free PMC article.
An in-depth analysis of these sets provided the following insights: (i) In the presence of a low extracellular substrate concentration, a transporter can only cycle at a high rate, if it has low values for both, the Michaelis-Menten constant (K(M)) for substrate and the ma …
An in-depth analysis of these sets provided the following insights: (i) In the presence of a low extracellular substrate concentration, a tr …
23 results