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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH, Abramova L, Adorjan K, Agerbo E, Al Eissa M, Albani D, Alliey-Rodriguez N, Anjorin A, Antilla V, Antoniou A, Awasthi S, Baek JH, Bækvad-Hansen M, Bass N, Bauer M, Beins EC, Bergen SE, Birner A, Bøcker Pedersen C, Bøen E, Boks MP, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cairns M, Casas M, Cervantes P, Clarke TK, Cruceanu C, Cuellar-Barboza A, Cunningham J, Curtis D, Czerski PM, Dale AM, Dalkner N, David FS, Degenhardt F, Djurovic S, Dobbyn AL, Douzenis A, Elvsåshagen T, Escott-Price V, Ferrier IN, Fiorentino A, Foroud TM, Forty L, Frank J, Frei O, Freimer NB, Frisén L, Gade K, Garnham J, Gelernter J, Giørtz Pedersen M, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha K, Haraldsson M, Hautzinger M, Heilbronner U, Hellgren D, Herms S, Hoffmann P, Holmans PA, Huckins L, Jamain S, Johnson JS, Kalman JL, Kamatani Y, Kennedy… See abstract for full author list ➔ Mullins N, et al. Nat Genet. 2021 Jun;53(6):817-829. doi: 10.1038/s41588-021-00857-4. Epub 2021 May 17. Nat Genet. 2021. PMID: 34002096 Free PMC article.
Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program.
Seyerle AA, Laurie CA, Coombes BJ, Jain D, Conomos MP, Brody J, Chen MH, Gogarten SM, Beutel KM, Gupta N, Heckbert SR, Jackson RD, Johnson AD, Ko D, Manson JE, McKnight B, Metcalf GA, Morrison AC, Reiner AP, Sofer T, Tang W, Wiggins KL; Trans-Omics for Precision Medicine Program; Boerwinkle E, de Andrade M, Gabriel SB, Gibbs RA, Laurie CC, Psaty BM, Vasan RS, Rice K, Kooperberg C, Pankow JS, Smith NL, Pankratz N. Seyerle AA, et al. Circ Genom Precis Med. 2023 Apr;16(2):e003532. doi: 10.1161/CIRCGEN.121.003532. Epub 2023 Mar 24. Circ Genom Precis Med. 2023. PMID: 36960714 Free PMC article.
Constraints on Lightly Ionizing Particles from CDMSlite.
Alkhatib I, Amaral DWP, Aralis T, Aramaki T, Arnquist IJ, Ataee Langroudy I, Azadbakht E, Banik S, Barker D, Bathurst C, Bauer DA, Bezerra LVS, Bhattacharyya R, Bowles MA, Brink PL, Bunker R, Cabrera B, Calkins R, Cameron RA, Cartaro C, Cerdeño DG, Chang YY, Chaudhuri M, Chen R, Chott N, Cooley J, Coombes H, Corbett J, Cushman P, De Brienne F, di Vacri ML, Diamond MD, Fascione E, Figueroa-Feliciano E, Fink CW, Fouts K, Fritts M, Gerbier G, Germond R, Ghaith M, Golwala SR, Harris HR, Hines BA, Hollister MI, Hong Z, Hoppe EW, Hsu L, Huber ME, Iyer V, Jardin D, Jastram A, Kashyap VKS, Kelsey MH, Kubik A, Kurinsky NA, Lawrence RE, Li A, Loer B, Lopez Asamar E, Lukens P, MacFarlane DB, Mahapatra R, Mandic V, Mast N, Mayer AJ, Meyer Zu Theenhausen H, Michaud ÉM, Michielin E, Mirabolfathi N, Mohanty B, Morales Mendoza JD, Nagorny S, Nelson J, Neog H, Novati V, Orrell JL, Oser SM, Page WA, Partridge R, Podviianiuk R, Ponce F, Poudel S, Pradeep A, Pyle M, Rau W, Reid E, Ren R, Reynolds T, Roberts A, Robinson AE, Saab T, Sadoulet B, Sander J, Sattari A, Schnee RW, Scorza S, Serfass B, Sincavage DJ, Stanford C, Street J, Toback D, Underwood R, Verma S, Villano AN, von Krosigk B, Watkins SL, … See abstract for full author list ➔ Alkhatib I, et al. Phys Rev Lett. 2021 Aug 20;127(8):081802. doi: 10.1103/PhysRevLett.127.081802. Phys Rev Lett. 2021. PMID: 34477436
We report first direct-detection limits calculated using the optimum interval method on the vertical intensity of cosmogenically produced LIPs with an electric charge smaller than e/(310^{5}), as well as the strongest limits for charge e/160, with a minimum vertical …
We report first direct-detection limits calculated using the optimum interval method on the vertical intensity of cosmogenically produced LI …
Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection.
Cuéllar-Barboza AB, McElroy SL, Veldic M, Singh B, Kung S, Romo-Nava F, Nunez NA, Cabello-Arreola A, Coombes BJ, Prieto M, Betcher HK, Moore KM, Winham SJ, Biernacka JM, Frye MA. Cuéllar-Barboza AB, et al. Int J Bipolar Disord. 2020 Jul 4;8(1):23. doi: 10.1186/s40345-020-00184-3. Int J Bipolar Disord. 2020. PMID: 32632502 Free PMC article. Review.
We summarize our findings in: targeted candidate genes of pharmacokinetic and pharmacodynamic pathways, genome-wide association studies and, PGT platforms, related to BD treatment. This field has grown from studies of metabolizing enzymes (i.e., pharmacokinetics) and drug …
We summarize our findings in: targeted candidate genes of pharmacokinetic and pharmacodynamic pathways, genome-wide association studies and, …
Long-Term Follow-Up of the Intergroup Exemestane Study.
Morden JP, Alvarez I, Bertelli G, Coates AS, Coleman R, Fallowfield L, Jassem J, Jones S, Kilburn L, Lønning PE, Ortmann O, Snowdon C, van de Velde C, Andersen J, Del Mastro L, Dodwell D, Holmberg S, Nicholas H, Paridaens R, Bliss JM, Coombes RC. Morden JP, et al. J Clin Oncol. 2017 Aug 1;35(22):2507-2514. doi: 10.1200/JCO.2016.70.5640. Epub 2017 May 3. J Clin Oncol. 2017. PMID: 28467729 Free PMC article. Clinical Trial.
Similar Morphological and Functional Training Adaptations Occur Between Continuous and Intermittent Blood Flow Restriction.
Davids CJ, Raastad T, James LP, Gajanand T, Smith E, Connick M, McGorm H, Keating S, Coombes JS, Peake JM, Roberts LA. Davids CJ, et al. J Strength Cond Res. 2021 Jul 1;35(7):1784-1793. doi: 10.1519/JSC.0000000000004034. J Strength Cond Res. 2021. PMID: 34027913
Davids, CJ, Raastad, T, James, L, Gajanand, T, Smith, E, Connick, M, McGorm, H, Keating, S, Coombes, JS, Peake, JM, and Roberts, LA. ...
Davids, CJ, Raastad, T, James, L, Gajanand, T, Smith, E, Connick, M, McGorm, H, Keating, S, Coombes, JS, Peake, JM, and …
Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci.
Huang XF, Li Z, De Guzman E, Robinson P, Gensler L, Ward MM, Rahbar MH, Lee M, Weisman MH, Macfarlane GJ, Jones GT, Klingberg E, Forsblad-d'Elia H, McCluskey P, Wakefield D, Coombes JS, Fiatarone Singh MA, Mavros Y, Vlahovich N, Hughes DC, Marzo-Ortega H, Van der Horste-Bruinsma I, O'Shea F, Martin TM, Rosenbaum J, Breban M, Jin ZB, Leo P, Reveille JD, Wordsworth BP, Brown MA. Huang XF, et al. Invest Ophthalmol Vis Sci. 2020 Jun 3;61(6):3. doi: 10.1167/iovs.61.6.3. Invest Ophthalmol Vis Sci. 2020. PMID: 32492107 Free PMC article.
42 results