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Extended-spectrum beta-lactamase-producing Enterobacteriaceae from animal origin and wastewater in Tunisia: first detection of O25b-B2(3)-CTX-M-27-ST131 Escherichia coli and CTX-M-15/OXA-204-producing Citrobacter freundii from wastewater.
Sghaier S, Abbassi MS, Pascual A, Serrano L, Díaz-De-Alba P, Said MB, Hassen B, Ibrahim C, Hassen A, López-Cerero L. Sghaier S, et al. J Glob Antimicrob Resist. 2019 Jun;17:189-194. doi: 10.1016/j.jgar.2019.01.002. Epub 2019 Jan 11. J Glob Antimicrob Resist. 2019. PMID: 30639890
RESULTS: A total of 81 E. coli, 20 K. pneumoniae, 4 Enterobacter cloacae, 1 Citrobacter freundii and 1 Citrobacter braakii were isolated. The bla(CTX-M-1) and bla(CTX-M-15) genes were predominant in E. coli and K. pneumoniae isolates. ...The K. pneumoniae isolates b …
RESULTS: A total of 81 E. coli, 20 K. pneumoniae, 4 Enterobacter cloacae, 1 Citrobacter freundii and 1 Citrobacter braakii were isolated. Th …
Prevalence of ST131 Clone Producing Both ESBL CTX-M-15 and AAC(6')Ib-cr Among Ciprofloxacin-Resistant Escherichia coli Isolates from Yemen.
Alsharapy SA, Yanat B, Lopez-Cerero L, Nasher SS, Díaz-De-Alba P, Pascual Á, Rodríguez-Martínez JM, Touati A. Alsharapy SA, et al. Microb Drug Resist. 2018 Dec;24(10):1537-1542. doi: 10.1089/mdr.2018.0024. Epub 2018 Jun 8. Microb Drug Resist. 2018. PMID: 29883247
Results: All E. coli isolates contained the aac(6')Ib-cr gene associated with bla(CTX-M-15) and qnrS genes in 63.4% and 12.2%, respectively. A rate of 36.6% (15/41) of O25b/ST131 E. coli isolates were identified belonging to the H30-Rx subclone producing both CTX-M- …
Results: All E. coli isolates contained the aac(6')Ib-cr gene associated with bla(CTX-M-15) and qnrS genes in 63.4% and 12.2%, respec …
Faecal carriage of extended-spectrum beta-lactamase-producing Escherichia coli: prevalence, risk factors and molecular epidemiology.
Rodríguez-Baño J, López-Cerero L, Navarro MD, Díaz de Alba P, Pascual A. Rodríguez-Baño J, et al. J Antimicrob Chemother. 2008 Nov;62(5):1142-9. doi: 10.1093/jac/dkn293. Epub 2008 Jul 18. J Antimicrob Chemother. 2008. PMID: 18641033
Among the relatives, multivariate analysis showed that those eating their main meal outside their own home >15 days during the previous month were less likely to be faecal carriers (OR = 0.2; 95% CI: 0.06-0.6; P = 0.007). The faecal isolates of patients with UTI were CTX-M …
Among the relatives, multivariate analysis showed that those eating their main meal outside their own home >15 days during the previous m …
Genetic characterization of an extended-spectrum AmpC cephalosporinase with hydrolysing activity against fourth-generation cephalosporins in a clinical isolate of Enterobacter aerogenes selected in vivo.
Rodríguez-Martínez JM, Fernández-Echauri P, Fernández-Cuenca F, Diaz de Alba P, Briales A, Pascual A. Rodríguez-Martínez JM, et al. J Antimicrob Chemother. 2012 Jan;67(1):64-8. doi: 10.1093/jac/dkr423. Epub 2011 Oct 16. J Antimicrob Chemother. 2012. PMID: 22001269
AmpC-Ea595 hydrolysed ceftazidime, cefepime and cefpirome at high levels, presenting a lower K(m) and enabling us to classify the enzyme as an ESAC. Homology modelling suggested that the size of the active site could have increased. ...
AmpC-Ea595 hydrolysed ceftazidime, cefepime and cefpirome at high levels, presenting a lower K(m) and enabling us to classify the enz …
Occurrence of the Plasmid-Mediated Fluoroquinolone Resistance qepA1 Gene in Two Clonal Clinical Isolates of CTX-M-15-Producing Escherichia coli from Algeria.
Yanat B, Dali Yahia R, Yazi L, Machuca J, Díaz-De-Alba P, Touati A, Pascual Á, Rodríguez-Martínez JM. Yanat B, et al. Microb Drug Resist. 2017 Jun;23(4):497-499. doi: 10.1089/mdr.2016.0135. Epub 2016 Oct 13. Microb Drug Resist. 2017. PMID: 27736309
This study describes, for the first time in Algeria, two clonally related, QepA-producing Escherichia coli clinical isolates positive for CTX-M-15. The clonal spread of these multidrug-resistant isolates is a major public health concern....
This study describes, for the first time in Algeria, two clonally related, QepA-producing Escherichia coli clinical isolates positive for CT …