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Circulating galectin-1 delineates response to bevacizumab in melanoma patients and reprograms endothelial cell biology.
Bannoud N, Stupirski JC, Cagnoni AJ, Hockl PF, Pérez Sáez JM, García PA, Mahmoud YD, Gambarte Tudela J, Scheidegger MA, Marshall A, Corrie PG, Middleton MR, Mariño KV, Girotti MR, Croci DO, Rabinovich GA. Bannoud N, et al. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2214350120. doi: 10.1073/pnas.2214350120. Epub 2023 Jan 12. Proc Natl Acad Sci U S A. 2023. PMID: 36634146 Free PMC article. Clinical Trial.
Here, we explored, in a cohort of melanoma patients from AVAST-M, a multicenter, open-label, randomized controlled phase 3 trial of adjuvant bevacizumab versus standard surveillance, the role of circulating plasma Gal1 as part of a compensatory mechanism that orchestrates …
Here, we explored, in a cohort of melanoma patients from AVAST-M, a multicenter, open-label, randomized controlled phase 3 trial of a …
The genome of a bunyavirus cannot be defined at the level of the viral particle but only at the scale of the viral population.
Yvon M, German TL, Ullman DE, Dasgupta R, Parker MH, Ben-Mahmoud S, Verdin E, Gognalons P, Ancelin A, Laï Kee Him J, Girard J, Vernerey MS, Fernandez E, Filloux D, Roumagnac P, Bron P, Michalakis Y, Blanc S. Yvon M, et al. Proc Natl Acad Sci U S A. 2023 Nov 28;120(48):e2309412120. doi: 10.1073/pnas.2309412120. Epub 2023 Nov 20. Proc Natl Acad Sci U S A. 2023. PMID: 37983500
Within virions, both plus and minus strands (but no mRNA) are packaged for each of the three L, M, and S segments, in reproducible nonequimolar proportions determined by those in total cell extracts. ...
Within virions, both plus and minus strands (but no mRNA) are packaged for each of the three L, M, and S segments, in reproducible no …
Nitrogen doped graphene quantum dots based on host guest interaction for selective dual readout of dopamine.
Mahmoud AM, Mahnashi MH, Alhazzani K, Az A, Algahtani MM, Alaseem A, Alyami BA, AlQarni AO, El-Wekil MM. Mahmoud AM, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2021 May 5;252:119516. doi: 10.1016/j.saa.2021.119516. Epub 2021 Feb 1. Spectrochim Acta A Mol Biomol Spectrosc. 2021. PMID: 33561682
Under the optimized conditions, the colorimetric method achieved linearity range of 0.12-7.5 M and LOD (S/N = 3) of 0.04 M, while the fluorometric method achieved linearity range of 0.028-1.5 M and LOD (S/N = 3) of 0.009 M. ...
Under the optimized conditions, the colorimetric method achieved linearity range of 0.12-7.5 M and LOD (S/N = 3) of 0.04 M, wh …
Ratiometric fluorescence sensing of hazardous ciprofloxacin based on aggregation induced emission enhancement of thiolate-protected gold nanoclusters induced by La3+ ion.
Mahmoud AM, Mahnashi MH, El-Wekil MM. Mahmoud AM, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Jan 5;304:123347. doi: 10.1016/j.saa.2023.123347. Epub 2023 Sep 5. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 37688885
Under optimized conditions, the fluorescence ratios (F(440)/F(610)) were linearly increased with increasing the CIPRO amount within the range of 0.003-200 M with a limit of detection equal to 0.2 nM (S/N = 3). The as-fabricated La(3+)/GSH@AuNCs system possesses outstanding …
Under optimized conditions, the fluorescence ratios (F(440)/F(610)) were linearly increased with increasing the CIPRO amount within the rang …
A reliable and selective ratiometric sensing probe for fluorometric determination of P2O74- based on AIE of GSH@CuNCs-assisted by Al-N@CQDs.
Mahmoud AM, Abu-Alrub SS, Al-Qarni AO, El-Wekil MM, Shahin RY. Mahmoud AM, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Apr 5;310:123850. doi: 10.1016/j.saa.2024.123850. Epub 2024 Jan 9. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 38219614
The response ratio (F(450)/F(620)) increased with increasing the concentration of P(2)O(7)(4-) in the range of 0.035-160 M, with an impressive detection limit of 0.012 M. This innovative approach of utilizing hybrid CQDs/thiolate-capped nanoclusters as a ratiometric …
The response ratio (F(450)/F(620)) increased with increasing the concentration of P(2)O(7)(4-) in the range of 0.035-160 M, with an i …
Ternary metal complexes of guaifenesin drug: Synthesis, spectroscopic characterization and in vitro anticancer activity of the metal complexes.
Mahmoud WH, Mahmoud NF, Mohamed GG, El-Sonbati AZ, El-Bindary AA. Mahmoud WH, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2015;150:451-60. doi: 10.1016/j.saa.2015.05.066. Epub 2015 May 29. Spectrochim Acta A Mol Biomol Spectrosc. 2015. PMID: 26067934
The ternary metal complexes were found to have the formulae of [M(GFS)(Phen)Cl]Cl.nH2O (M=Cr(III) (n=1) and Fe(III) (n=0)), [M(GFS)(Phen)Cl].nH2O (M=Mn(II) (n=0), Zn(II) (n=0) and Cu(II) (n=3)) and [M(GFS)(Phen)(H2O)]Cl.nH2O (M=Co(II) (n= …
The ternary metal complexes were found to have the formulae of [M(GFS)(Phen)Cl]Cl.nH2O (M=Cr(III) (n=1) and Fe(III) (n=0)), [ …
Investigation of isomeric structures in a commercial mixture of naphthenic acids using ultrahigh pressure liquid chromatography coupled to hybrid traveling wave ion mobility-time of flight mass spectrometry.
Yassine MM, Dabek-Zlotorzynska E. Yassine MM, et al. J Chromatogr A. 2018 Oct 19;1572:90-99. doi: 10.1016/j.chroma.2018.08.052. Epub 2018 Aug 24. J Chromatogr A. 2018. PMID: 30172356
Fifty seven standard compounds belonging to different chemical families of classical NAs were analyzed to obtain their experimental drift times in addition to chromatographic retention time and mass-to-charge information (m/z). These acyclic and cyclic molecules yielded io …
Fifty seven standard compounds belonging to different chemical families of classical NAs were analyzed to obtain their experimental drift ti …
Techno-economic assessment of waste mandarin biochar as a green adsorbent for binary dye wastewater effluents of methylene blue and basic fuchsin: Lab- and large-scale investigations.
El-Shafie AS, Rahman E, GadelHak Y, Mahmoud R, El-Azazy M. El-Shafie AS, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Feb 5;306:123621. doi: 10.1016/j.saa.2023.123621. Epub 2023 Nov 7. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 37950932
The cost of MRBC was estimated to be 4 USD/kg, while the overall cost of wastewater treatment was estimated to be 1.06 USD/m(3)/year....
The cost of MRBC was estimated to be 4 USD/kg, while the overall cost of wastewater treatment was estimated to be 1.06 USD/m(3)/year. …
Ligational behaviour of lomefloxacin drug towards Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Th(IV) and UO(2)(VI) ions: synthesis, structural characterization and biological activity studies.
Abd el-Halim HF, Mohamed GG, el-Dessouky MM, Mahmoud WH. Abd el-Halim HF, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Nov;82(1):8-19. doi: 10.1016/j.saa.2011.05.089. Epub 2011 Jun 1. Spectrochim Acta A Mol Biomol Spectrosc. 2011. PMID: 21855402
The dissociation constants of lomefloxacin and stability constants of its binary complexes have been determined spectrophotometrically in aqueous solution at 251C and at 0.1 M KNO(3) ionic strength. The discussion of the outcome data of the prepared complexes indicate that …
The dissociation constants of lomefloxacin and stability constants of its binary complexes have been determined spectrophotometrically in aq …