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Showing results for maris strands
Your search for Māris Strazds retrieved no results
The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression.
Maris C, Dominguez C, Allain FH. Maris C, et al. FEBS J. 2005 May;272(9):2118-31. doi: 10.1111/j.1742-4658.2005.04653.x. FEBS J. 2005. PMID: 15853797 Free article. Review.
Outside of the two conserved RNP motifs that lie in the center of the RRM beta-sheet, the two external beta-strands, the loops, the C- and N-termini, or even a second RRM domain allow high RNA-binding affinity and specific recognition. ...
Outside of the two conserved RNP motifs that lie in the center of the RRM beta-sheet, the two external beta-strands, the loops, the C …
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, Gray JW, Guinney J, Hanlon SE, Hughes SK, Hwang ES, Iacobuzio-Donahue CA, Jané-Valbuena J, Johnson BE, Lau KS, Lively T, Mazzilli SA, Pe'er D, Santagata S, Shalek AK, Schapiro D, Snyder MP, Sorger PK, Spira AE, Srivastava S, Tan K, West RB, Williams EH; Human Tumor Atlas Network. Rozenblatt-Rosen O, et al. Cell. 2020 Apr 16;181(2):236-249. doi: 10.1016/j.cell.2020.03.053. Cell. 2020. PMID: 32302568 Free PMC article. Review.
Epigenetic state determines inflammatory sensing in neuroblastoma.
Wolpaw AJ, Grossmann LD, Dessau JL, Dong MM, Aaron BJ, Brafford PA, Volgina D, Pascual-Pasto G, Rodriguez-Garcia A, Uzun Y, Arsenian-Henriksson M, Powell DJ Jr, Bosse KR, Kossenkov A, Tan K, Hogarty MD, Maris JM, Dang CV. Wolpaw AJ, et al. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2102358119. doi: 10.1073/pnas.2102358119. Proc Natl Acad Sci U S A. 2022. PMID: 35121657 Free PMC article.
By testing the functional response of a panel of 20 diverse neuroblastoma cell lines to three different inflammatory stimuli, we found that all cell lines have intact interferon signaling, and all but one lack functional cytosolic DNA sensing via cGAS-STING. However, double-st …
By testing the functional response of a panel of 20 diverse neuroblastoma cell lines to three different inflammatory stimuli, we found that …
MITI minimum information guidelines for highly multiplexed tissue images.
Schapiro D, Yapp C, Sokolov A, Reynolds SM, Chen YA, Sudar D, Xie Y, Muhlich J, Arias-Camison R, Arena S, Taylor AJ, Nikolov M, Tyler M, Lin JR, Burlingame EA; Human Tumor Atlas Network; Chang YH, Farhi SL, Thorsson V, Venkatamohan N, Drewes JL, Pe'er D, Gutman DA, Herrmann MD, Gehlenborg N, Bankhead P, Roland JT, Herndon JM, Snyder MP, Angelo M, Nolan G, Swedlow JR, Schultz N, Merrick DT, Mazzili SA, Cerami E, Rodig SJ, Santagata S, Sorger PK. Schapiro D, et al. Nat Methods. 2022 Mar;19(3):262-267. doi: 10.1038/s41592-022-01415-4. Nat Methods. 2022. PMID: 35277708 Free PMC article.
Inhibiting immunoregulatory amidase NAAA blocks ZIKV maturation in Human Neural Stem Cells.
Lai M, La Rocca V, Iacono E, Filipponi C, De Carli A, Favaro D, Fonnesu R, Filippini F, Spezia PG, Amato R, Catelli E, Matteo B, Lottini G, Onorati M, Clementi N, Freer G, Piomelli D, Pistello M. Lai M, et al. Antiviral Res. 2023 Aug;216:105664. doi: 10.1016/j.antiviral.2023.105664. Epub 2023 Jul 4. Antiviral Res. 2023. PMID: 37414288 Free article.
This discovery prompted us to hypothesize that interference with lipogenesis could serve as a dual antiviral and anti-inflammatory strategy to combat the replication of positive sense single-stranded RNA (ssRNA+) viruses. To test this hypothesis, we examined the impact of …
This discovery prompted us to hypothesize that interference with lipogenesis could serve as a dual antiviral and anti-inflammatory strategy …
BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma.
Randall MP, Egolf LE, Vaksman Z, Samanta M, Tsang M, Groff D, Evans JP, Rokita JL, Layeghifard M, Shlien A, Maris JM, Diskin SJ, Bosse KR. Randall MP, et al. J Natl Cancer Inst. 2024 Jan 10;116(1):138-148. doi: 10.1093/jnci/djad182. J Natl Cancer Inst. 2024. PMID: 37688570
BARD1 loss-of-function variant isogenic cells exhibited reduced efficiency in repairing Cas9-induced DNA damage, ineffective RAD51 focus formation at DNA double-strand break sites, and enhanced sensitivity to cisplatin and poly (ADP-ribose) polymerase (PARP) inhibition bot …
BARD1 loss-of-function variant isogenic cells exhibited reduced efficiency in repairing Cas9-induced DNA damage, ineffective RAD51 focus for …
MicroRNAs in oral fluids (saliva and gingival crevicular fluid) as biomarkers in orthodontics: systematic review and integrated bioinformatic analysis.
Kapoor P, Chowdhry A, Bagga DK, Bhargava D, Aishwarya S. Kapoor P, et al. Prog Orthod. 2021 Oct 11;22(1):31. doi: 10.1186/s40510-021-00377-1. Prog Orthod. 2021. PMID: 34632546 Free PMC article. Review.
BACKGROUND: MicroRNAs (miRNAs) are non-coding short, single-stranded RNA molecules that may serve as biomarkers for various inflammatory and molecular mechanisms underlying bone and tissue remodeling consequent to orthodontic force application. ...
BACKGROUND: MicroRNAs (miRNAs) are non-coding short, single-stranded RNA molecules that may serve as biomarkers for various inflammat …
Functional Network Profiles in ARSACS Disclosed by Aptamer-Based Proteomic Technology.
Morani F, Doccini S, Chiorino G, Fattori F, Galatolo D, Sciarrillo E, Gemignani F, Züchner S, Bertini ES, Santorelli FM. Morani F, et al. Front Neurol. 2021 Jan 27;11:603774. doi: 10.3389/fneur.2020.603774. eCollection 2020. Front Neurol. 2021. PMID: 33584503 Free PMC article.
In this study, we analyzed proteomics data obtained using the SomaLogic technology, comparing cell lysates from ARSACS patients and from a SACS KO SH-SY5Y neuroblastoma cell model. Single-stranded deoxyoligonucleotides, selected in vitro from large random libraries, bound …
In this study, we analyzed proteomics data obtained using the SomaLogic technology, comparing cell lysates from ARSACS patients and from a S …
Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains.
Masliah G, Maris C, König SL, Yulikov M, Aeschimann F, Malinowska AL, Mabille J, Weiler J, Holla A, Hunziker J, Meisner-Kober N, Schuler B, Jeschke G, Allain FH. Masliah G, et al. EMBO J. 2018 Mar 15;37(6):e97089. doi: 10.15252/embj.201797089. Epub 2018 Feb 15. EMBO J. 2018. PMID: 29449323 Free PMC article.
The accurate cleavage of pre-micro(mi)RNAs by Dicer and mi/siRNA guide strand selection are important steps in forming the RNA-induced silencing complex (RISC). ...
The accurate cleavage of pre-micro(mi)RNAs by Dicer and mi/siRNA guide strand selection are important steps in forming the RNA-induce …
30 results