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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1884 1
1898 1
1899 2
1931 1
1945 2
1946 9
1947 4
1948 8
1949 2
1950 12
1951 11
1952 23
1953 8
1954 13
1955 16
1956 15
1957 15
1958 19
1959 11
1960 5
1961 6
1962 6
1963 43
1964 67
1965 25
1966 6
1967 11
1968 15
1969 15
1970 14
1971 17
1972 12
1973 14
1974 13
1975 19
1976 12
1977 15
1978 33
1979 25
1980 34
1981 42
1982 53
1983 65
1984 71
1985 75
1986 104
1987 129
1988 149
1989 164
1990 209
1991 279
1992 284
1993 354
1994 367
1995 416
1996 428
1997 425
1998 466
1999 526
2000 614
2001 634
2002 725
2003 844
2004 974
2005 1122
2006 1189
2007 1222
2008 1368
2009 1474
2010 1633
2011 1858
2012 1979
2013 2318
2014 2435
2015 2434
2016 2475
2017 2681
2018 2718
2019 2993
2020 3586
2021 4135
2022 4239
2023 3768
2024 1530

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50,342 results

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The following term was not found in PubMed: Monika-Anetta
Page 1
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.
Yadav T, Zhang JM, Ouyang J, Leung W, Simoneau A, Zou L. Yadav T, et al. Mol Cell. 2022 Nov 3;82(21):3985-4000.e4. doi: 10.1016/j.molcel.2022.09.026. Epub 2022 Oct 19. Mol Cell. 2022. PMID: 36265486 Free PMC article.
Alternative lengthening of telomeres (ALT), a telomerase-independent process maintaining telomeres, is mediated by break-induced replication (BIR). RAD52 promotes ALT by facilitating D-loop formation, but ALT also occurs through a RAD52-independent BIR pathwa …
Alternative lengthening of telomeres (ALT), a telomerase-independent process maintaining telomeres, is mediated by break-induced repl …
Laser Trabeculoplasty.
Shaw E, Gupta P. Shaw E, et al. 2023 Mar 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Mar 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 35201703 Free Books & Documents.
Wise and Witter described the first protocol for argon laser trabeculoplasty in 1979. They demonstrated the safety and efficacy of ALT in a group of patients with open-angle glaucoma (OAG). The safety and long-term efficacy of ALT were studied in the Glaucoma Laser …
Wise and Witter described the first protocol for argon laser trabeculoplasty in 1979. They demonstrated the safety and efficacy of ALT …
Alternative paths to telomere elongation.
Lee JJ, Lee J, Lee H. Lee JJ, et al. Semin Cell Dev Biol. 2021 May;113:88-96. doi: 10.1016/j.semcdb.2020.11.003. Epub 2020 Dec 5. Semin Cell Dev Biol. 2021. PMID: 33293233 Review.
However, a subset of cancers takes an alternate route for elongating telomeres: recombination-based alternative lengthening of telomeres (ALT). Current evidence suggests that break-induced replication (BIR), independent of RAD51, underlies ALT telomere synthesis. .. …
However, a subset of cancers takes an alternate route for elongating telomeres: recombination-based alternative lengthening of telomeres ( …
Clinical progress of auxiliary liver transplantation.
Li J, Tian DZ, Jiang WT, Shen ZY. Li J, et al. Eur J Gastroenterol Hepatol. 2021 Jan;33(1):4-8. doi: 10.1097/MEG.0000000000001751. Eur J Gastroenterol Hepatol. 2021. PMID: 32398492 Review.
After half a century of development, auxiliary liver transplantation (ALT) technology gradually matured and major indications of ALT have been gradually expanded. ...Additionally, the expansion of indications for ALT which included the implementation of AL …
After half a century of development, auxiliary liver transplantation (ALT) technology gradually matured and major indications of A …
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway.
Carson LM, Flynn RL. Carson LM, et al. Curr Opin Pharmacol. 2023 Jun;70:102380. doi: 10.1016/j.coph.2023.102380. Epub 2023 May 5. Curr Opin Pharmacol. 2023. PMID: 37149932 Review.
This results in an elevated level of DNA damage and presents a possible vulnerability to be exploited in the development of ALT-targeted cancer therapies. Currently, there are no treatment options that target the ALT mechanism or that are specific for ALT-pos …
This results in an elevated level of DNA damage and presents a possible vulnerability to be exploited in the development of ALT-targe …
ALT Positivity in Human Cancers: Prevalence and Clinical Insights.
MacKenzie D Jr, Watters AK, To JT, Young MW, Muratori J, Wilkoff MH, Abraham RG, Plummer MM, Zhang D. MacKenzie D Jr, et al. Cancers (Basel). 2021 May 14;13(10):2384. doi: 10.3390/cancers13102384. Cancers (Basel). 2021. PMID: 34069193 Free PMC article. Review.
We first briefly review and assess a variety of commonly used ALT biomarkers. Then, we provide both an update on ALT-positive (ALT+) tumor prevalence as well as a systematic clinical assessment of the presently studied ALT+ malignancies. Additionally, …
We first briefly review and assess a variety of commonly used ALT biomarkers. Then, we provide both an update on ALT-positive …
The Pedicled Anterolateral Thigh Phalloplasty.
Xu KY, Watt AJ. Xu KY, et al. Clin Plast Surg. 2018 Jul;45(3):399-406. doi: 10.1016/j.cps.2018.03.011. Epub 2018 May 1. Clin Plast Surg. 2018. PMID: 29908629 Review.
The anterolateral thigh (ALT) flap is a viable and reliable option for phalloplasty. The primary advantages of the ALT flap remain an inconspicuous donor site and flexibility in phallus length. ...Careful patient selection is paramount in attaining acceptable result …
The anterolateral thigh (ALT) flap is a viable and reliable option for phalloplasty. The primary advantages of the ALT flap re …
Prevalence of Elevated ALT in Adolescents in the US 2011-2018.
Mischel AK, Liao Z, Cao F, Dunn W, Lo JC, Newton KP, Goyal NP, Yu EL, Schwimmer JB. Mischel AK, et al. J Pediatr Gastroenterol Nutr. 2023 Jul 1;77(1):103-109. doi: 10.1097/MPG.0000000000003795. Epub 2023 Apr 21. J Pediatr Gastroenterol Nutr. 2023. PMID: 37084344
Elevated ALT thresholds up to 2X-ULN were examined among adolescents with obesity. ...Asian adolescents with elevated BMI may comprise an emerging risk group for elevated ALT....
Elevated ALT thresholds up to 2X-ULN were examined among adolescents with obesity. ...Asian adolescents with elevated BMI may compris …
Telomere elongation chooses TERRA ALTernatives.
Arora R, Azzalin CM. Arora R, et al. RNA Biol. 2015;12(9):938-41. doi: 10.1080/15476286.2015.1065374. RNA Biol. 2015. PMID: 26158306 Free PMC article. Review.
ALT is naturally active in a number of human cancers and might be selected upon telomerase inactivation. ...Indeed, suppression of a number of HR factors impairs ALT cell proliferation. Yet, how HR is initiated at ALT telomeres remains elusive. ...
ALT is naturally active in a number of human cancers and might be selected upon telomerase inactivation. ...Indeed, suppression of a …
Recent Advancement in Atypical Lipomatous Tumor Research.
Mashima E, Sawada Y, Nakamura M. Mashima E, et al. Int J Mol Sci. 2021 Jan 20;22(3):994. doi: 10.3390/ijms22030994. Int J Mol Sci. 2021. PMID: 33498189 Free PMC article. Review.
As one of the important issues for clinicians, it is a hot topic of how to distinguish ALT from benign lipoma in the clinical aspect. Recent studies revealed novel findings to clarify the risk factor for the diagnosis of ALT and molecular targets for the treatment o …
As one of the important issues for clinicians, it is a hot topic of how to distinguish ALT from benign lipoma in the clinical aspect. …
50,342 results
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