Mónika Vastag - Search Results

Year	Number of Results
2004	1
2005	2
2008	1
2009	2
2010	2
2011	1
2012	3
2013	2
2014	2
2015	2
2016	5
2017	2
2018	2
2019	3
2020	2
2021	5
2022	2
2023	2
2024	2

1

Transendothelial Electrical Resistance Measurement across the Blood-Brain Barrier: A Critical Review of Methods.

Vigh JP, Kincses A, Ozgür B, Walter FR, Santa-Maria AR, Valkai S, Vastag M, Neuhaus W, Brodin B, Dér A, Deli MA. Vigh JP, et al. Among authors: vastag m. Micromachines (Basel). 2021 Jun 11;12(6):685. doi: 10.3390/mi12060685. Micromachines (Basel). 2021. PMID: 34208338 Free PMC article. Review.

2

Cell-based models of blood-brain barrier penetration.

Vastag M, Hellinger E, Bakk ML, Tihanyi K. Vastag M, et al. Ther Deliv. 2011 May;2(5):549-53. doi: 10.4155/tde.11.35. Ther Deliv. 2011. PMID: 22833973 No abstract available.

3

Current in vitro and in silico models of blood-brain barrier penetration: a practical view.

Vastag M, Keseru GM. Vastag M, et al. Curr Opin Drug Discov Devel. 2009 Jan;12(1):115-24. Curr Opin Drug Discov Devel. 2009. PMID: 19152220 Review.

4

Multiparameter Optimization of Naphthyridine Derivatives as Selective α5-GABA_A Receptor Negative Allosteric Modulators.

Szabó G, Éliás O, Erdélyi P, Potor A, Túrós GI, Károlyi BI, Varró G, Vaskó ÁG, Bata I, Kapus GL, Dohányos Z, Bobok AÁ, Fodor L, Thán M, Vastag M, Komlódi Z, Soukupné Kedves RÉ, Makó É, Süveges B, Greiner I. Szabó G, et al. Among authors: vastag m. J Med Chem. 2022 Jun 9;65(11):7876-7895. doi: 10.1021/acs.jmedchem.2c00414. Epub 2022 May 18. J Med Chem. 2022. PMID: 35584373

5

Human cerebral microvessel endothelial cell culture as a model system to study the blood-brain interface in ischemic/hypoxic conditions.

Nagy Z, Vastag M, Kolev K, Bori Z, Karáidi I, Skopál J. Nagy Z, et al. Among authors: vastag m. Cell Mol Neurobiol. 2005 Feb;25(1):201-10. doi: 10.1007/s10571-004-1384-9. Cell Mol Neurobiol. 2005. PMID: 15962514 Review.

6

Identification of Triazolopyridines as Selective α5-GABA_A Receptor Negative Allosteric Modulators by a Hybridization Approach.

Szabó G, Károlyi BI, Vaskó ÁG, Potor A, Vukics K, Kapus GL, Fodor L, Bobok A, Vastag M, Bata I. Szabó G, et al. Among authors: vastag m. ACS Chem Neurosci. 2023 Jan 4;14(1):148-158. doi: 10.1021/acschemneuro.2c00608. Epub 2022 Dec 16. ACS Chem Neurosci. 2023. PMID: 36524695

7

Discovery of Novel Steroid-Based Histamine H₃ Receptor Antagonists/Inverse Agonists.

Ledneczki I, Tapolcsányi P, Gábor E, Éles J, Barabás J, Béni Z, Varga B, Balázs O, Román V, Fodor L, Szikra J, Vastag M, Lévay G, Schmidt É, Lendvai B, Greiner I, Kiss B, Némethy Z, Mahó S. Ledneczki I, et al. Among authors: vastag m. J Med Chem. 2024 Mar 14;67(5):3643-3667. doi: 10.1021/acs.jmedchem.3c02117. Epub 2024 Feb 23. J Med Chem. 2024. PMID: 38393759

8

Fragment-Based Optimization of Dihydropyrazino-Benzimidazolones as Metabotropic Glutamate Receptor-2 Positive Allosteric Modulators against Migraine.

Szabó G, Erdélyi P, Kolok S, Vastag M, Halász AS, Kis-Varga I, Lévay GI, Béni Z, Kóti J, Greiner I, Keserű GM. Szabó G, et al. Among authors: vastag m. J Med Chem. 2021 Jun 24;64(12):8607-8620. doi: 10.1021/acs.jmedchem.1c00563. Epub 2021 Jun 3. J Med Chem. 2021. PMID: 34080424

9

Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560).

Ledneczki I, Némethy Z, Molnár KD, Tapolcsányi P, Ilkei V, Vágó I, Kolok S, Thán M, Laszy J, Balázs O, Krámos B, Szigetvári Á, Bata I, Makó A, Visegrády A, Fodor L, Vastag M, Lévay G, Lendvai B, Greiner I, Éles J. Ledneczki I, et al. Among authors: vastag m. J Med Chem. 2023 Dec 14;66(23):16276-16302. doi: 10.1021/acs.jmedchem.3c01635. Epub 2023 Nov 21. J Med Chem. 2023. PMID: 37989278

10

Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs).

Szabó G, Kolok S, Orgován Z, Vastag M, Béni Z, Kóti J, Sághy K, Lévay GI, Greiner I, Keserű GM. Szabó G, et al. Among authors: vastag m. Eur J Med Chem. 2020 Jan 15;186:111881. doi: 10.1016/j.ejmech.2019.111881. Epub 2019 Nov 15. Eur J Med Chem. 2020. PMID: 31780081

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