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Silencing miR-370-3p rescues funny current and sinus node function in heart failure.
Yanni J, D'Souza A, Wang Y, Li N, Hansen BJ, Zakharkin SO, Smith M, Hayward C, Whitson BA, Mohler PJ, Janssen PML, Zeef L, Choudhury M, Zi M, Cai X, Logantha SJRJ, Nakao S, Atkinson A, Petkova M, Doris U, Ariyaratnam J, Cartwright EJ, Griffiths-Jones S, Hart G, Fedorov VV, Oceandy D, Dobrzynski H, Boyett MR. Yanni J, et al. Among authors: petkova m. Sci Rep. 2020 Jul 9;10(1):11279. doi: 10.1038/s41598-020-67790-0. Sci Rep. 2020. PMID: 32647133 Free PMC article.
Atrioventricular Node Dysfunction and Ion Channel Transcriptome in Pulmonary Hypertension.
Temple IP, Logantha SJ, Absi M, Zhang Y, Pervolaraki E, Yanni J, Atkinson A, Petkova M, Quigley GM, Castro S, Drinkhill M, Schneider H, Monfredi O, Cartwright E, Zi M, Yamanushi TT, Mahadevan VS, Gurney AM, White E, Zhang H, Hart G, Boyett MR, Dobrzynski H. Temple IP, et al. Among authors: petkova m. Circ Arrhythm Electrophysiol. 2016 Dec;9(12):e003432. doi: 10.1161/CIRCEP.115.003432. Circ Arrhythm Electrophysiol. 2016. PMID: 27979911 Free PMC article.
Identification of Key Small Non-Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node.
Petkova M, Atkinson AJ, Yanni J, Stuart L, Aminu AJ, Ivanova AD, Pustovit KB, Geragthy C, Feather A, Li N, Zhang Y, Oceandy D, Perde F, Molenaar P, D'Souza A, Fedorov VV, Dobrzynski H. Petkova M, et al. J Am Heart Assoc. 2020 Oct 20;9(20):e016590. doi: 10.1161/JAHA.120.016590. Epub 2020 Oct 16. J Am Heart Assoc. 2020. PMID: 33059532 Free PMC article.
Further insights into the molecular complexity of the human sinus node - The role of 'novel' transcription factors and microRNAs.
Aminu AJ, Petkova M, Atkinson AJ, Yanni J, Morris AD, Simms RT, Chen W, Yin Z, Kuniewicz M, Holda MK, Kuzmin VS, Perde F, Molenaar P, Dobrzynski H. Aminu AJ, et al. Among authors: petkova m. Prog Biophys Mol Biol. 2021 Nov;166:86-104. doi: 10.1016/j.pbiomolbio.2021.04.008. Epub 2021 May 15. Prog Biophys Mol Biol. 2021. PMID: 34004232 Free article.
Micro-RNA 133a-3p induces repolarization abnormalities in atrial myocardium and modulates ventricular electrophysiology affecting ICa,L and Ito currents.
Kuzmin VS, Ivanova AD, Filatova TS, Pustovit KB, Kobylina AA, Atkinson AJ, Petkova M, Voronkov YI, Abramochkin DV, Dobrzynski H. Kuzmin VS, et al. Among authors: petkova m. Eur J Pharmacol. 2021 Oct 5;908:174369. doi: 10.1016/j.ejphar.2021.174369. Epub 2021 Jul 24. Eur J Pharmacol. 2021. PMID: 34310913 Free article.